Ab119767

antibody from Aladdin Scientific

Targeting: P4HB DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PO4DB, PO4HB, PROHB

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Validation data

Product number: Ab119767 - Provider product page
Provider: Aladdin Scientific
Product name: P4HB Antibody
Antibody type: Polyclonal
Description: Rabbit anti Human P4HB Antibody, Polyclonal, could be used for WB and so on.Application: WB: 0.5-2 µg/mLProtein FunctionThis multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: AA 216-465
Vial size: 100_l,10_l,1ml,20_l,50_l
Concentration: Lot by Lot
Storage: Store at 4¡C short term (1-2 weeks). Store at -20¡C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

P4HB protein structure - Ab119767 shown in red.