Ab119767

antibody from Aladdin Scientific Corporation

Targeting: P4HB DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PO4DB, PO4HB, PROHB

Western blot (Data presented on provider website)

Antibody Data

Product number

Ab119767

Provider

Aladdin Scientific Corporation

Product name

P4HB Antibody

Antibody type

Polyclonal

Description

Rabbit anti Human P4HB Antibody, Polyclonal, could be used for WB and so on.Application:WB: 0.5-2 µg/mLProtein FunctionThis multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

AA 216-465


Vial size

100μl,10μl,1ml,20μl,50μl

Concentration

Lot by Lot

Storage

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.