BS7872

antibody from Bioworld Technology, Inc
Targeting: ATG3 APG3L, DKFZp564M1178, FLJ22125, MGC15201, PC3-96
Provider product page for BS7872
Western blot
Immunohistochemistry

Antibody data

Product number
BS7872 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ATG3 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human ATG3.
Description
Atg3 (autophagy-related protein 3), also known as APG3-like, hAPG3 or PC3-96, is an E2-like enzyme that localizes to the cytoplasm and is expressed in a variety of tissues with predominant levels found in kidney, placenta, liver, heart and skeletal muscle. Atg3 catalyzes the formation of the Atg8-phosphatidylethanolamine (Atg8-PE) conjugate, a reaction that is essential for autophagy (a cellular process that allows for the degradation of organelles and bulk cellular proteins). The process of forming the Atg8-PE conjugate begins with the removal of the C-terminal arginine residue of Atg8 by Atg4, a cysteine protease. The, now exposed, glycine residue is then activated by Atg7 and is then transferred to Atg3 for the final conjugation to PE. This last step can be accelerated by the presence of the Atg12-Atg5 conjugate which functions similarly to an E3 enzyme.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ATG3 protein structure - BS7872 shown in red.