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Protein structure
EHMT1
Euchromatic histone lysine methyltransferase 1bA188C12.1, EHMT1-IT1, Eu-HMTase1, FLJ12879, FLJ40292, KIAA1876, KMT1D
The protein encoded by this gene is a histone methyltransferase that methylates the lysine-9 position of histone H3. This action marks the genomic region packaged with these methylated histones for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]
Top validated antibodies |
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| Novus Biologicals |  PP-B0422-00 |
9 references | Monoclonal |
WB
EL
IP
IHC
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| R&D Systems | PP-B0422-00 |
9 references | Monoclonal |
WB
EL
IP
IHC
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| antibodies-online | ABIN2869188 |
1 references | Monoclonal |
WB
EL
IHC
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| LSBio | LS-C342545 |
Monoclonal |
WB
ICC
|
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| BioLegend | 601901 |
2 references | Polyclonal |
WB
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