abx027882

antibody from Abbexa

Targeting: TMC6 EVER1, EVIN1, LAK-4P, TNRC6C-AS1

Western blot (Recommended by provider)

Antibody Data

Product number

abx027882

Provider

Abbexa

Product name

Transmembrane Channel-Like Protein 6 (TMC6) Antibody

Antibody type

Polyclonal

Description

Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

80 µl

Concentration

0.45 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.