ABIN350218

antibody from antibodies-online

Targeting: CLCN1 ClC-1, CLC1

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN350218

Provider

antibodies-online

Proper citation

Antibodies-Online Cat#ABIN350218, RRID:AB_10781261

Product name

anti-Chloride Channel 1, Skeletal Muscle (CLCN1) (N-Term) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide from the n-terminal region of human Chloride channel protein 1 (CLCN1) conjugated to an immunogenic carrier protein was used as the antigen.

Description

Whole serum

Reactivity

Human

Host

Rabbit

Epitope

N-Term

Vial size

100 μL

Storage

Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Handling

Avoid freeze and thaw cycles.

References

Submitted references

Myotonia levior is a chloride channel disorder.

Lehmann-Horn F, Mailänder V, Heine R, George AL
Human molecular genetics 1995 Aug;4(8):1397-402

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Genomic organization of the human muscle chloride channel CIC-1 and analysis of novel mutations leading to Becker-type myotonia.

Lorenz C, Meyer-Kleine C, Steinmeyer K, Koch MC, Jentsch TJ
Human molecular genetics 1994 Jun;3(6):941-6

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Multimeric structure of ClC-1 chloride channel revealed by mutations in dominant myotonia congenita (Thomsen).

Steinmeyer K, Lorenz C, Pusch M, Koch MC, Jentsch TJ
The EMBO journal 1994 Feb 15;13(4):737-43

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The skeletal muscle chloride channel in dominant and recessive human myotonia.

Koch MC, Steinmeyer K, Lorenz C, Ricker K, Wolf F, Otto M, Zoll B, Lehmann-Horn F, Grzeschik KH, Jentsch TJ
Science (New York, N.Y.) 1992 Aug 7;257(5071):797-800