11418-2-AP

antibody from Proteintech Group

Targeting: COX5B

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

11418-2-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#11418-2-AP, RRID:AB_2245376

Product name

COX5B antibody

Antibody type

Polyclonal

Description

KD/KO validated COX5B antibody (Cat. #11418-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Global mitochondrial protein import proteomics reveal distinct regulation by translation and translocation machinery.

Schäfer JA, Bozkurt S, Michaelis JB, Klann K, Münch C
Molecular cell 2021 Nov 19;

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O-GlcNAcylation on Rab3A attenuates its effects on mitochondrial oxidative phosphorylation and metastasis in hepatocellular carcinoma.

Wu W, Zheng X, Wang J, Yang T, Dai W, Song S, Fang L, Wang Y, Gu J
Cell death & disease 2018 Sep 20;9(10):970

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The mitochondrial TMEM177 associates with COX20 during COX2 biogenesis.

Lorenzi I, Oeljeklaus S, Aich A, Ronsör C, Callegari S, Dudek J, Warscheid B, Dennerlein S, Rehling P
Biochimica et biophysica acta. Molecular cell research 2018 Feb;1865(2):323-333

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Enhanced Respiratory Chain Supercomplex Formation in Response to Exercise in Human Skeletal Muscle.

Greggio C, Jha P, Kulkarni SS, Lagarrigue S, Broskey NT, Boutant M, Wang X, Conde Alonso S, Ofori E, Auwerx J, Cantó C, Amati F
Cell metabolism 2017 Feb 7;25(2):301-311

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Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense.

Garaude J, Acín-Pérez R, Martínez-Cano S, Enamorado M, Ugolini M, Nistal-Villán E, Hervás-Stubbs S, Pelegrín P, Sander LE, Enríquez JA, Sancho D
Nature immunology 2016 Sep;17(9):1037-1045

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Mitochondrial Protein Synthesis Adapts to Influx of Nuclear-Encoded Protein.

Richter-Dennerlein R, Oeljeklaus S, Lorenzi I, Ronsör C, Bareth B, Schendzielorz AB, Wang C, Warscheid B, Rehling P, Dennerlein S
Cell 2016 Oct 6;167(2):471-483.e10

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Mechanism of super-assembly of respiratory complexes III and IV.

Cogliati S, Calvo E, Loureiro M, Guaras AM, Nieto-Arellano R, Garcia-Poyatos C, Ezkurdia I, Mercader N, Vázquez J, Enriquez JA
Nature 2016 Nov 24;539(7630):579-582

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Analysis of the mitochondrial proteome in multiple sclerosis cortex.

Broadwater L, Pandit A, Clements R, Azzam S, Vadnal J, Sulak M, Yong VW, Freeman EJ, Gregory RB, McDonough J
Biochimica et biophysica acta 2011 May;1812(5):630-41

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Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain.

Oliva CR, Nozell SE, Diers A, McClugage SG 3rd, Sarkaria JN, Markert JM, Darley-Usmar VM, Bailey SM, Gillespie GY, Landar A, Griguer CE
The Journal of biological chemistry 2010 Dec 17;285(51):39759-67

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

mouse liver tissue were subjected to SDS PAGE followed by western blot with 11418-2-AP(COX5B antibody) at dilution of 1:1000

Sample type

tissue

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of MCF-7 cells, using COX5B antibody 11418-2-AP at 1:50 antibody and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human gliomas using 11418-2-AP(COX5B antibody) at dilution of 1:50 (under 10x lens)

Sample type

tissue