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Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
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- Western blot [1]
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- Product number
- BS9125 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- HC II (D68) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 41-90 of Human HC-II.
- Description
- Heparin cofactor II (HCII) is a glycoprotein in human plasma which rapidly inactivates Thrombin in the presence of dermatan sulfate. Inhibition occurs by formation of a stable equimolar complex between HCII and Thrombin. Certain clinical conditions, such as hepatic failure, disseminated intravascular coagulation, thalasemina and sickle cell anemia, display reduced levels of HCII. However, during pregnancy, physiological levels of HCII expression are elevated. HCII may regulate coagulation and may participate in processes such as inflammation, atherosclerosis and wound repair. HCII is widely distributed among vertebrates and may have a common function in birds, amphibians and mammals.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of HC-II (D68) pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:Raw264.7 whole cell lysateLane3:PC12 whole cell lysate
