BS8203

antibody from Bioworld Technology, Inc
Targeting: TPD52L1 D53, hD53, TPD53
Provider product page for BS8203
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8203 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TPD52L1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human TPD52L1.
Description
The cell commits to dividing during the G2/M phase transition, and the timing of mitotic entry is tightly regulated to guarantee correct chromosome segregation. D53, also referred to as tumor protein D52-like 1 (TPD52L1), is a coiled-coil motif-bearing member of the D52 tumor protein family. D53 intereacts with 14-3-3, a negative regulator of the G2/M transition, in breast cancer cells. Expression of D53 is highly upregulated at the G2/M phase transition in breast cancer cell lines, and deregulated expression of this protein can adversely affect the completion of mitosis. D53 may function as a signaling intermediate and/or regulator of vesicle trafficking and cell proliferation.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TPD52L1 protein structure - BS8203 shown in red.