Tissue expression
Cell line expression
Protein structure
UPK1B
Uroplakin 1BTSPAN20, UPK1
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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antibodies-online | ![]() |
3 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
1 references | Polyclonal |
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GeneTex | ![]() |
Polyclonal |
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Boster Biological Technology | ![]() |
Polyclonal |
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OriGene | ![]() |
Polyclonal |
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