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LearnBS8342
antibody from Bioworld Technology, Inc
Targeting: NLRP12
CLR19.3, Monarch1, NALP12, PAN6, PYPAF7, RNO2
Western blotAntibody data
- Antibody Data
- Antigen structure
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- Product number
- BS8342 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- NLRP12 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human NLRP12.
- Description
- Pyrin-containing Apaf1-like proteins (PYPAFs) are members of the nucleotide-binding site/leucine-rich repeat (NBS/LRR) family of signal transduction proteins that function in apoptotic and inflammatory signaling pathways. PYPAF7, also known as Monarch-1, regulates activation of caspase-1 via ASC protein and promotes activation of NF-kappa-B via IKK. PYPAF7 enhances nonclassical and classical MHC class I expression at the level of the promoter, RNA, and protein expression. PYPAF7 is present in the cytoplasm of peripheral blood leukocytes, predominantly eosinophils and granulocytes, with lower levels in monocytes. The PYPAF7 gene maps to human chromosome 19q13.4.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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