BS8235

antibody from Bioworld Technology, Inc
Targeting: TFPT amida, FB1, INO80F
Provider product page for BS8235
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8235 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TFPT polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human TFPT.
Description
TFPT (TCF3 fusion partner), also known as INO80F or protein FB1, is a 253 amino acid nuclear protein. TFPT is a component of the chromatin-remoldeling INO80 complex, which is composed of proteins such as BAF53, ACTR5, ACTR8, INOC1, INO80B, INO80C, INO80D and INO80E. The INO80 complex, in addition to chromatin-remoldeling, plays a role in DNA repair, DNA replication, checkpoint regulation, telomere maintenance and chromosome segregation. TFPT interacts with ARC and appears to promote apoptosis in a TP53/p53-independent manner. It is also thought that a chromosomal aberration involving the genes that encode TFPT and E2A is a cause of pre-B-cell acute lymphoblastic leukemia (B-ALL).
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TFPT protein structure - BS8235 shown in red.