BS6306

antibody from Bioworld Technology, Inc
Targeting: EIF5B DKFZp434I036, FLJ10524, IF2, KIAA0741
Provider product page for BS6306
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6306 - Provider product page
Provider
Bioworld Technology, Inc
Product name
EIF5B polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human EIF5B.
Description
In mammalian cells, translation is controlled at the level of polypeptide chain initiation by initiation factors. The eukaryotic translation initiation factor 5 (eIF5) catalyzes the hydrolysis of GTP bound to the 40S ribosomal subunit, a function necessary for the subsequent joining of the 40S and 60S subunits to form the 80S initiation complex. eIF5B (Eukaryotic translation initiation factor 5B), also known as Translation initiation factor IF-2, is a 1,120 amino acid cytoplasmic protein that functions in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. eIF5B interacts with Annexin V, an anticoagulant protein, in a calcium and phospholipid-dependent manner. Since eIF5B is conserved among all three kingdoms of life, it is also known as an universal initiation factor.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
EIF5B protein structure - BS6306 shown in red.