FNab00082

antibody from FineTest Biotech
Targeting: TUBA1A B-ALPHA-1, FLJ25113, TUBA3
Provider product page for FNab00082
Western blot
ELISA
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
FNab00082 - Provider product page
Provider
FineTest Biotech
Product name
Acetylated tubulin (Lys40) antibody
Antibody type
Monoclonal
Antigen
Recombinant protein fragment
Description
Tubulin, composed of heterodimers of alpha and beta tubulin, is the mainly component of microtubules which play important roles in cell motility, mitosis, and intracellular vesicle transport. Both alpha and beta tubulin undergo several posttranslational modifications such as polyglutamylation and acetylation/deacetylation. Tubulin acetylation occurs on lysine-40 at the N-terminal of alpha tubulin and is conserved across species. The histone deacetylase HDAC6 and SIRT2 has been identified as tubulin deacetylases. Reversible acetylation of alpha tubulin may be implicated in regulating microtubule stability, cell motility, and axon regeneration. The level of acetylated tubulin has been linked to epithelial malignancies and sensitivity to chemotherapy. In addition, acetylated tubulin has been widely used as a marker for primary cilia. This antibody is specific to the acetylated tubulin; it does not recognize non-acetylated tubulin.
Reactivity
Human, Mouse, Rat, Canine
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
tubulin, alpha 1a
Epitope
IgG1
Isotype
IgG
Antibody clone number
6A10
Vial size
100¦Ìg
Concentration
Protein A+G purification
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
TUBA1A protein structure - FNab00082 shown in red.