Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BS7783 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- CYP4A11 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human CYP4A11.
- Description
- Cytochrome P450 proteins are heme-thiolate monooxygenases that mediate NADPH-dependent electron transport and function to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Specifically, Cytochrome P450s are responsible for metabolizing arachidonic acid to hydroxyeicosatetraenoic acid (a regulator of blood pressure) and epoxyeicosatrienoic acid (a molecule involved in signaling events). Cytochrome P450 4A11 (CYP4A11), also known as CP4Y, CYP4A2, P450HL-Àß or CYP4AII, is a 519 amino acid protein that is expressed in kidney and liver. Localized to the membrane of the endoplasmic reticulum, CYP4A11 uses heme as a cofactor to catalyze the oxygen-dependent hydroxylation of medium-chain fatty acids, such as myristate, laurate and palmitate, thereby playing an important role in fatty acid metabolism. CYP4A11 exists as two isoforms that are produced by alternative splicing events.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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