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Western blot
Blocking/NeutralizingAntibody data
- Antibody Data
- Antigen structure
- References [8]
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- Validations
- Blocking/Neutralizing [1]
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- Product number
- AF2325 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal Chemerin Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects mouse Chemerin in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 20% cross-reactivity with recombinant human Chemerin is observed.
- Reactivity
- Mouse
- Host
- Goat
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Pro- and Anti-Inflammatory Role of ChemR23 Signaling in Pollutant-Induced Inflammatory Lung Responses.
Targeting VEGF-A in myeloid cells enhances natural killer cell responses to chemotherapy and ameliorates cachexia.
The expression and regulation of chemerin in the epidermis.
Chemerin neutralization blocks hematopoietic stem cell osteoclastogenesis.
The role of ChemR23 in the induction and resolution of cigarette smoke-induced inflammation.
Chemerin, a novel peroxisome proliferator-activated receptor gamma (PPARgamma) target gene that promotes mesenchymal stem cell adipogenesis.
Chemerin peptides promote phagocytosis in a ChemR23- and Syk-dependent manner.
Mouse ChemR23 is expressed in dendritic cell subsets and macrophages, and mediates an anti-inflammatory activity of chemerin in a lung disease model.
Provoost S, De Grove KC, Fraser GL, Lannoy VJ, Tournoy KG, Brusselle GG, Maes T, Joos GF
Journal of immunology (Baltimore, Md. : 1950) 2016 Feb 15;196(4):1882-90
Journal of immunology (Baltimore, Md. : 1950) 2016 Feb 15;196(4):1882-90
Targeting VEGF-A in myeloid cells enhances natural killer cell responses to chemotherapy and ameliorates cachexia.
Klose R, Krzywinska E, Castells M, Gotthardt D, Putz EM, Kantari-Mimoun C, Chikdene N, Meinecke AK, Schrödter K, Helfrich I, Fandrey J, Sexl V, Stockmann C
Nature communications 2016 Aug 19;7:12528
Nature communications 2016 Aug 19;7:12528
The expression and regulation of chemerin in the epidermis.
Banas M, Zegar A, Kwitniewski M, Zabieglo K, Marczynska J, Kapinska-Mrowiecka M, LaJevic M, Zabel BA, Cichy J
PloS one 2015;10(2):e0117830
PloS one 2015;10(2):e0117830
Chemerin neutralization blocks hematopoietic stem cell osteoclastogenesis.
Muruganandan S, Dranse HJ, Rourke JL, McMullen NM, Sinal CJ
Stem cells (Dayton, Ohio) 2013 Oct;31(10):2172-82
Stem cells (Dayton, Ohio) 2013 Oct;31(10):2172-82
The role of ChemR23 in the induction and resolution of cigarette smoke-induced inflammation.
Demoor T, Bracke KR, Dupont LL, Plantinga M, Bondue B, Roy MO, Lannoy V, Lambrecht BN, Brusselle GG, Joos GF
Journal of immunology (Baltimore, Md. : 1950) 2011 May 1;186(9):5457-67
Journal of immunology (Baltimore, Md. : 1950) 2011 May 1;186(9):5457-67
Chemerin, a novel peroxisome proliferator-activated receptor gamma (PPARgamma) target gene that promotes mesenchymal stem cell adipogenesis.
Muruganandan S, Parlee SD, Rourke JL, Ernst MC, Goralski KB, Sinal CJ
The Journal of biological chemistry 2011 Jul 8;286(27):23982-95
The Journal of biological chemistry 2011 Jul 8;286(27):23982-95
Chemerin peptides promote phagocytosis in a ChemR23- and Syk-dependent manner.
Cash JL, Christian AR, Greaves DR
Journal of immunology (Baltimore, Md. : 1950) 2010 May 1;184(9):5315-24
Journal of immunology (Baltimore, Md. : 1950) 2010 May 1;184(9):5315-24
Mouse ChemR23 is expressed in dendritic cell subsets and macrophages, and mediates an anti-inflammatory activity of chemerin in a lung disease model.
Luangsay S, Wittamer V, Bondue B, De Henau O, Rouger L, Brait M, Franssen JD, de Nadai P, Huaux F, Parmentier M
Journal of immunology (Baltimore, Md. : 1950) 2009 Nov 15;183(10):6489-99
Journal of immunology (Baltimore, Md. : 1950) 2009 Nov 15;183(10):6489-99
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Chemotaxis Induced by Chemerin and Neutralization by Mouse Chemerin Antibody. Chemotaxis Induced by Chemerin and Neutralization by Mouse Chemerin Antibody.
