BS1975

antibody from Bioworld Technology, Inc

Targeting: CMPK1 CMPK, UMP-CMPK

Immunohistochemistry

Antibody data

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Validation data

Product number: BS1975 - Provider product page
Provider: Bioworld Technology, Inc
Product name: UMP CMP Kinase (E36) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic peptide, corresponding to the N-terminal of Human UMP-CMP Kinase.
Description: Nucleoside monophosphate kinases are required for pharmacological activation of therapeutic nucleosides and nucleotide analogs. CMPK (Cytidine monophosphate kinase), also known as UMP-CMP kinase and Deoxycytidylate kinase, is a 196 amino acid protein that catalyzes the phosphoryl transfer from ATP to UMP, CMP and dCMP. This enzymatic reaction leads to the formation of ADP and the corresponding nucleoside diphosphate, which are required for cellular nucleic acid synthesis. Primarily localized to the cytoplasm, CMPK also plays an important role in the activation of pyrimidine analogs, which is clinically useful anti-cancer and anti-viral drugs. CMP is the best substrate for CMPK, followed by UMP and dCMP.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

CMPK1 protein structure - BS1975 shown in red.