abx003606

antibody from Abbexa

Targeting: SPA17 CT22, SP17

Western blot (Recommended by provider)

Antibody Data

Product number

abx003606

Provider

Abbexa

Product name

Sperm Surface Protein Sp17 (SPA17) Antibody

Antibody type

Polyclonal

Description

SPA17 Antibody is a Rabbit Polyclonal antibody against SPA17. This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

> 1 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.