PAB6879

antibody from Abnova Corporation

Targeting: ENPP1 M6S1, NPPS, PC-1, PCA1, PDNP1

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB6879

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB6879, RRID:AB_1574682

Product name

ENPP1 polyclonal antibody

Antibody type

Polyclonal

Description

Goat polyclonal antibody raised against synthetic peptide of ENPP1.

Antigen sequence

C-KTHLPTFSQED


Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Decreased levels of nucleotide pyrophosphatase phosphodiesterase 1 are associated with cartilage calcification in osteoarthritis and trigger osteoarthritic changes in mice.

Bertrand J, Nitschke Y, Fuerst M, Hermann S, Schäfers M, Sherwood J, Nalesso G, Ruether W, Rutsch F, Dell'Accio F, Pap T
Annals of the rheumatic diseases 2012 Jul;71(7):1249-53

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Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes.

Meyre D, Bouatia-Naji N, Tounian A, Samson C, Lecoeur C, Vatin V, Ghoussaini M, Wachter C, Hercberg S, Charpentier G, Patsch W, Pattou F, Charles MA, Tounian P, Clément K, Jouret B, Weill J, Maddux BA, Goldfine ID, Walley A, Boutin P, Dina C, Froguel P
Nature genetics 2005 Aug;37(8):863-7

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

HEK293 overexpressing Human ENPP1 and probed with ENPP1 polyclonal antibody (Cat # PAB6879) (mock transfection in first lane) .

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

ENPP1 polyclonal antibody (Cat # PAB6879) (1 ug/mL) staining of paraffin embedded human liver. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining.

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)