PA3-860

antibody from Invitrogen Antibodies

Targeting: KCNH2 erg1, HERG, Kv11.1, LQT2

Immunocytochemistry (Supportive data in Antibodypedia)

Other assay (Supportive data in Antibodypedia)

Antibody Data

Product number

PA3-860

Provider

Invitrogen Antibodies

Product name

KCNH2 Polyclonal Antibody

Antibody type

Polyclonal

Antigen

Other

Description

PA3-860 detects HERG in human samples.

Concentration

Conc. Not Determined

References

Submitted references

ZC88, a novel 4-amino piperidine analog, inhibits the growth of neuroblastoma cells through blocking hERG potassium channel.

Wei X, Sun H, Yan H, Zhang C, Zhang S, Liu X, Hua N, Ma X, Zheng J
Cancer biology & therapy 2013 May;14(5):450-7

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Chronic inhibition of cardiac Kir2.1 and HERG potassium channels by celastrol with dual effects on both ion conductivity and protein trafficking.

Sun H, Liu X, Xiong Q, Shikano S, Li M
The Journal of biological chemistry 2006 Mar 3;281(9):5877-84

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HERG channel dysfunction in human long QT syndrome. Intracellular transport and functional defects.

Zhou Z, Gong Q, Epstein ML, January CT
The Journal of biological chemistry 1998 Aug 14;273(33):21061-6

Immunocytochemistry

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunofluorescence staining of HERG in HEK 293 cells using Product # PA3-860.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunofluorescence staining of HERG in HEK 293 cells using Product # PA3-860.

Other assay

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

NULL

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

NULL