Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 16117-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16117-1-AP, RRID:AB_2176154
- Product name
- RAC1/2/3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RAC1/2/3 antibody (Cat. #16117-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Gangliosides in the differentiation process of primary neurons: the specific role of GM1-oligosaccharide.
A Method to Culture GABAergic Interneurons Derived from the Medial Ganglionic Eminence.
Phosphorylated cortactin recruits Vav2 guanine nucleotide exchange factor to activate Rac3 and promote invadopodial function in invasive breast cancer cells.
Identification of a Protein Network Driving Neuritogenesis of MGE-Derived GABAergic Interneurons.
Silencing of Rac3 inhibits proliferation and induces apoptosis of human lung cancer cells.
F-box protein complex FBXL19 regulates TGFβ1-induced E-cadherin down-regulation by mediating Rac3 ubiquitination and degradation.
Rac3 induces a molecular pathway triggering breast cancer cell aggressiveness: differences in MDA-MB-231 and MCF-7 breast cancer cell lines.
Di Biase E, Lunghi G, Fazzari M, Maggioni M, Pomè DY, Valsecchi M, Samarani M, Fato P, Ciampa MG, Prioni S, Mauri L, Sonnino S, Chiricozzi E
Glycoconjugate journal 2020 Jun;37(3):329-343
Glycoconjugate journal 2020 Jun;37(3):329-343
A Method to Culture GABAergic Interneurons Derived from the Medial Ganglionic Eminence.
Franchi SA, Macco R, Astro V, Tonoli D, Savino E, Valtorta F, Sala K, Botta M, de Curtis I
Frontiers in cellular neuroscience 2017;11:423
Frontiers in cellular neuroscience 2017;11:423
Phosphorylated cortactin recruits Vav2 guanine nucleotide exchange factor to activate Rac3 and promote invadopodial function in invasive breast cancer cells.
Rosenberg BJ, Gil-Henn H, Mader CC, Halo T, Yin T, Condeelis J, Machida K, Wu YI, Koleske AJ
Molecular biology of the cell 2017 May 15;28(10):1347-1360
Molecular biology of the cell 2017 May 15;28(10):1347-1360
Identification of a Protein Network Driving Neuritogenesis of MGE-Derived GABAergic Interneurons.
Franchi SA, Astro V, Macco R, Tonoli D, Barnier JV, Botta M, de Curtis I
Frontiers in cellular neuroscience 2016;10:289
Frontiers in cellular neuroscience 2016;10:289
Silencing of Rac3 inhibits proliferation and induces apoptosis of human lung cancer cells.
Liu TQ, Wang GB, Li ZJ, Tong XD, Liu HX
Asian Pacific journal of cancer prevention : APJCP 2015;16(7):3061-5
Asian Pacific journal of cancer prevention : APJCP 2015;16(7):3061-5
F-box protein complex FBXL19 regulates TGFβ1-induced E-cadherin down-regulation by mediating Rac3 ubiquitination and degradation.
Dong S, Zhao J, Wei J, Bowser RK, Khoo A, Liu Z, Luketich JD, Pennathur A, Ma H, Zhao Y
Molecular cancer 2014 Apr 1;13:76
Molecular cancer 2014 Apr 1;13:76
Rac3 induces a molecular pathway triggering breast cancer cell aggressiveness: differences in MDA-MB-231 and MCF-7 breast cancer cell lines.
Gest C, Joimel U, Huang L, Pritchard LL, Petit A, Dulong C, Buquet C, Hu CQ, Mirshahi P, Laurent M, Fauvel-Lafève F, Cazin L, Vannier JP, Lu H, Soria J, Li H, Varin R, Soria C
BMC cancer 2013 Feb 6;13:63
BMC cancer 2013 Feb 6;13:63
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 16117-1-AP(RAC1/2/3 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using RAC3 antibody 16117-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 16117-1-AP(RAC1/2/3 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 16117-1-AP(RAC1/2/3 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue