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- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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- Product number
- 20772-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20772-1-AP, RRID:AB_10695765
- Product name
- LIMS1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated LIMS1 antibody (Cat. #20772-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The RNA-binding protein RBMS3 inhibits the progression of colon cancer by regulating the stability of LIMS1 mRNA.
PINCH-1 promotes IGF-1 receptor expression and skin cancer progression through inhibition of the GRB10-NEDD4 complex.
PINCH-1 promotes Δ(1)-pyrroline-5-carboxylate synthase expression and contributes to proline metabolic reprogramming in lung adenocarcinoma.
PINCH-1 regulates mitochondrial dynamics to promote proline synthesis and tumor growth.
A PINCH-1-Smurf1 signaling axis mediates mechano-regulation of BMPR2 and stem cell differentiation.
Differences in binding to the ILK complex determines kindlin isoform adhesion localization and integrin activation.
Li Y, Wang S, Li G, Gao C, Cui Z, Cong M, Hu J, Zhang M, Jin X, Sun H, Kong D
Cancer medicine 2024 Apr;13(7):e7129
Cancer medicine 2024 Apr;13(7):e7129
PINCH-1 promotes IGF-1 receptor expression and skin cancer progression through inhibition of the GRB10-NEDD4 complex.
Wang X, Wang R, Jiang K, Zhu M, Guo L, Wu C
Theranostics 2022;12(6):2613-2630
Theranostics 2022;12(6):2613-2630
PINCH-1 promotes Δ(1)-pyrroline-5-carboxylate synthase expression and contributes to proline metabolic reprogramming in lung adenocarcinoma.
Cui C, Wang J, Guo L, Wu C
Amino acids 2021 Dec;53(12):1875-1890
Amino acids 2021 Dec;53(12):1875-1890
PINCH-1 regulates mitochondrial dynamics to promote proline synthesis and tumor growth.
Guo L, Cui C, Wang J, Yuan J, Yang Q, Zhang P, Su W, Bao R, Ran J, Wu C
Nature communications 2020 Oct 1;11(1):4913
Nature communications 2020 Oct 1;11(1):4913
A PINCH-1-Smurf1 signaling axis mediates mechano-regulation of BMPR2 and stem cell differentiation.
Guo L, Wang R, Zhang K, Yuan J, Wang J, Wang X, Ma J, Wu C
The Journal of cell biology 2019 Nov 4;218(11):3773-3794
The Journal of cell biology 2019 Nov 4;218(11):3773-3794
Differences in binding to the ILK complex determines kindlin isoform adhesion localization and integrin activation.
Huet-Calderwood C, Brahme NN, Kumar N, Stiegler AL, Raghavan S, Boggon TJ, Calderwood DA
Journal of cell science 2014 Oct 1;127(Pt 19):4308-21
Journal of cell science 2014 Oct 1;127(Pt 19):4308-21
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human kidney tissue were subjected to SDS PAGE followed by western blot with 20772-1-AP(LIMS1 antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using LIMS1 antibody 20772-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human oesophagus cancer using 20772-1-AP(LIMS1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human oesophagus cancer using 20772-1-AP(LIMS1 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LIMS1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human LIMS1. This antibody recognizes human,mouse,rat antigen. The LIMS1 antibody has been validated for the following applications: ELISA, WB, IF, IHC, FC analysis.
