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- Antibody Data
- Antigen structure
- References [8]
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- Western blot [3]
- ELISA [1]
- Immunocytochemistry [1]
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- Product number
- H00010049-M01 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00010049-M01, RRID:AB_538330
- Product name
- Mouse Monoclonal DNAJB6 Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. DNAJB6 - DnaJ (Hsp40) homolog, subfamily B, member 6
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Mutations in the J domain of DNAJB6 cause dominant distal myopathy.
The Short Isoform of DNAJB6 Protects against 1-Methyl-4-phenylpridinium Ion-Induced Apoptosis in LN18 Cells via Inhibiting Both ROS Formation and Mitochondrial Membrane Potential Loss.
A modifier screen identifies DNAJB6 as a cardiomyopathy susceptibility gene.
Myofibrillar disruption and RNA-binding protein aggregation in a mouse model of limb-girdle muscular dystrophy 1D.
Myopathy-causing mutations in an HSP40 chaperone disrupt processing of specific client conformers.
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.
Interaction between urokinase receptor and heat shock protein MRJ enhances cell adhesion.
Interaction between urokinase receptor and heat shock protein MRJ enhances cell adhesion.
Palmio J, Jonson PH, Inoue M, Sarparanta J, Bengoechea R, Savarese M, Vihola A, Jokela M, Nakagawa M, Noguchi S, Olivé M, Masingue M, Kerty E, Hackman P, Weihl CC, Nishino I, Udd B
Neuromuscular disorders : NMD 2020 Jan;30(1):38-46
Neuromuscular disorders : NMD 2020 Jan;30(1):38-46
The Short Isoform of DNAJB6 Protects against 1-Methyl-4-phenylpridinium Ion-Induced Apoptosis in LN18 Cells via Inhibiting Both ROS Formation and Mitochondrial Membrane Potential Loss.
Hong YM, Hong Y, Choi YG, Yeo S, Jin SH, Lee SW, Sung B, Lee SH, Jung H, Lim S
Oxidative medicine and cellular longevity 2017;2017:7982389
Oxidative medicine and cellular longevity 2017;2017:7982389
A modifier screen identifies DNAJB6 as a cardiomyopathy susceptibility gene.
Ding Y, Long PA, Bos JM, Shih YH, Ma X, Sundsbak RS, Chen J, Jiang Y, Zhao L, Hu X, Wang J, Shi Y, Ackerman MJ, Lin X, Ekker SC, Redfield MM, Olson TM, Xu X
JCI insight 2016 Sep 8;1(14)
JCI insight 2016 Sep 8;1(14)
Myofibrillar disruption and RNA-binding protein aggregation in a mouse model of limb-girdle muscular dystrophy 1D.
Bengoechea R, Pittman SK, Tuck EP, True HL, Weihl CC
Human molecular genetics 2015 Dec 1;24(23):6588-602
Human molecular genetics 2015 Dec 1;24(23):6588-602
Myopathy-causing mutations in an HSP40 chaperone disrupt processing of specific client conformers.
Stein KC, Bengoechea R, Harms MB, Weihl CC, True HL
The Journal of biological chemistry 2014 Jul 25;289(30):21120-30
The Journal of biological chemistry 2014 Jul 25;289(30):21120-30
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.
Blandin G, Marchand S, Charton K, Danièle N, Gicquel E, Boucheteil JB, Bentaib A, Barrault L, Stockholm D, Bartoli M, Richard I
Skeletal muscle 2013 Feb 15;3(1):3
Skeletal muscle 2013 Feb 15;3(1):3
Interaction between urokinase receptor and heat shock protein MRJ enhances cell adhesion.
De Bock CE, Lin Z, Mekkawy AH, Byrne JA, Wang Y
International journal of oncology 2010 May;36(5):1155-63
International journal of oncology 2010 May;36(5):1155-63
Interaction between urokinase receptor and heat shock protein MRJ enhances cell adhesion.
De Bock CE, Lin Z, Mekkawy AH, Byrne JA, Wang Y
International journal of oncology 2010 May;36(5):1155-63
International journal of oncology 2010 May;36(5):1155-63
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: DNAJB6 Antibody (2C11-C1) [H00010049-M01] - Analysis of DNAJB6 expression in transfected 293T cell line by DNAJB6 monoclonal antibody (M01), clone 2C11-C1.Lane 1: DNAJB6 transfected lysate(27 KDa).Lane 2: Non-transfected lysate.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: DNAJB6 Antibody (2C11-C1) [H00010049-M01] - DNAJB6 monoclonal antibody (M01), clone 2C11-C1 Analysis of DNAJB6 expression in Jurkat.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: DNAJB6 Antibody (2C11-C1) [H00010049-M01] - DNAJB6 monoclonal antibody (M01), clone 2C11-C1. Analysis of DNAJB6 expression in C32.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- ELISA: DNAJB6 Antibody (2C11-C1) [H00010049-M01] - Detection limit for recombinant GST tagged DNAJB6 is approximately 1ng/ml as a capture antibody.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunocytochemistry/Immunofluorescence: DNAJB6 Antibody (2C11-C1) [H00010049-M01] - Analysis of monoclonal antibody to DNAJB6 on HeLa cell. Antibody concentration 10 ug/ml.
