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LearnH00050848-M01
antibody from Novus Biologicals
Targeting: F11R
CD321, JAM-1, JAM-A, JAM1, JAMA, JCAM, PAM-1
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [2]
- ELISA [2]
- Immunohistochemistry [1]
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- Product number
- H00050848-M01 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00050848-M01, RRID:AB_539968
- Product name
- Mouse Monoclonal JAM-A Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. F11R - F11 receptor
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references A perfusion bioreactor-based 3D model of the subarachnoid space based on a meningeal tissue construct.
Natural compound Tetrocarcin-A downregulates Junctional Adhesion Molecule-A in conjunction with HER2 and inhibitor of apoptosis proteins and inhibits tumor cell growth.
Estrogen reinforces barrier formation and protects against tumor necrosis factor alpha-induced barrier dysfunction in oral epithelial cells.
Cell-Cell Interaction Proteins (Gap Junctions, Tight Junctions, and Desmosomes) and Water Transporter Aquaporin 4 in Meningothelial Cells of the Human Optic Nerve.
Low junctional adhesion molecule A expression correlates with poor prognosis in gastric cancer.
Low expression of junctional adhesion molecule A is associated with metastasis and poor survival in pancreatic cancer.
JAM-A expression positively correlates with poor prognosis in breast cancer patients.
Downregulation of junctional adhesion molecule-A is involved in the progression of clear cell renal cell carcinoma.
Neutzner A, Power L, Dürrenberger M, Scholl HPN, Meyer P, Killer HE, Wendt D, Kohler C
Fluids and barriers of the CNS 2019 Jun 13;16(1):17
Fluids and barriers of the CNS 2019 Jun 13;16(1):17
Natural compound Tetrocarcin-A downregulates Junctional Adhesion Molecule-A in conjunction with HER2 and inhibitor of apoptosis proteins and inhibits tumor cell growth.
Vellanki SH, Cruz RGB, Jahns H, Hudson L, Sette G, Eramo A, Hopkins AM
Cancer letters 2019 Jan;440-441:23-34
Cancer letters 2019 Jan;440-441:23-34
Estrogen reinforces barrier formation and protects against tumor necrosis factor alpha-induced barrier dysfunction in oral epithelial cells.
Choi YS, Baek K, Choi Y
Journal of periodontal & implant science 2018 Oct;48(5):284-294
Journal of periodontal & implant science 2018 Oct;48(5):284-294
Cell-Cell Interaction Proteins (Gap Junctions, Tight Junctions, and Desmosomes) and Water Transporter Aquaporin 4 in Meningothelial Cells of the Human Optic Nerve.
Zeleny TNC, Kohler C, Neutzner A, Killer HE, Meyer P
Frontiers in neurology 2017;8:308
Frontiers in neurology 2017;8:308
Low junctional adhesion molecule A expression correlates with poor prognosis in gastric cancer.
Huang JY, Xu YY, Sun Z, Wang ZN, Zhu Z, Song YX, Luo Y, Zhang X, Xu HM
The Journal of surgical research 2014 Dec;192(2):494-502
The Journal of surgical research 2014 Dec;192(2):494-502
Low expression of junctional adhesion molecule A is associated with metastasis and poor survival in pancreatic cancer.
Fong D, Spizzo G, Mitterer M, Seeber A, Steurer M, Gastl G, Brosch I, Moser P
Annals of surgical oncology 2012 Dec;19(13):4330-6
Annals of surgical oncology 2012 Dec;19(13):4330-6
JAM-A expression positively correlates with poor prognosis in breast cancer patients.
McSherry EA, McGee SF, Jirstrom K, Doyle EM, Brennan DJ, Landberg G, Dervan PA, Hopkins AM, Gallagher WM
International journal of cancer 2009 Sep 15;125(6):1343-51
International journal of cancer 2009 Sep 15;125(6):1343-51
Downregulation of junctional adhesion molecule-A is involved in the progression of clear cell renal cell carcinoma.
Gutwein P, Schramme A, Voss B, Abdel-Bakky MS, Doberstein K, Ludwig A, Altevogt P, Hansmann ML, Moch H, Kristiansen G, Pfeilschifter J
Biochemical and biophysical research communications 2009 Mar 6;380(2):387-91
Biochemical and biophysical research communications 2009 Mar 6;380(2):387-91
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: JAM-A Antibody (2E3-1C8) [H00050848-M01] - Analysis of F11R expression in transfected 293T cell line by F11R monoclonal antibody (M01), clone 2E3-1C8. Lane 1: F11R transfected lysate (Predicted MW: 32.6 KDa). Lane 2: Non-transfected lysate.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: JAM-A Antibody (2E3-1C8) [H00050848-M01] - F11R monoclonal antibody (M01), clone 2E3-1C8 Analysis of F11R expression in HepG2.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- ELISA: JAM-A Antibody (2E3-1C8) [H00050848-M01] - Detection limit for recombinant GST tagged F11R is approximately 0.3ng/ml as a capture antibody.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Sandwich ELISA: JAM-A Antibody (2E3-1C8) [H00050848-M01] - Detection limit for recombinant GST tagged F11R is approximately 0.1ng/ml as a capture antibody.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: JAM-A Antibody (2E3-1C8) [H00050848-M01] - Analysis of monoclonal antibody to F11R on formalin-fixed paraffin-embedded human breast cancer tissue. Antibody concentration 1 ug/ml.
