Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-L790 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Rabbit Anti-CEBPA monoclonal antibody, clone TE313-10
- Antibody type
- Monoclonal
- Description
- The transcription factor C/EBP Ï« (CCAAT-enhancer binding protein) is a heat-stable, sequence-specific DNA-binding protein that binds avidly to several different cis-regulatory DNA sequences commonly associated with viral and cellular genes transcribed by RNA polymerase II. C/EBP Ï« regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP Ï« is a basic region/leucine zipper transcription factor selectively expressed during the differentiation of liver, adipose tissue, blood cells and the endocrine pancreas. C/EBP Ï« uses a bipartite structural motif to bind DNA and appears to function exclusively in terminally differentiated, growth-arrested cells. In the liver, C/EBP Ï« is a transactivator of several genes, which are regulated by growth hormone. Growth hormone enhances not only the levels of C/EBP Ï« mRNA and protein, but also the DNA binding activity of C/EBP Ï«. C/EBP Ï« functions as an important transcription factor that regulates different genes, including prolactin gene expression.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- TE313-10
- Vial size
- 100 _l
- Storage
- Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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