Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 10471-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10471-1-AP, RRID:AB_2091446
- Product name
- DHCR24 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DHCR24 antibody (Cat. #10471-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Golgi-Dependent Copper Homeostasis Sustains Synaptic Development and Mitochondrial Content.
Efferocytosis potentiates the expression of arachidonate 15-lipoxygenase (ALOX15) in alternatively activated human macrophages through LXR activation.
Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis.
Dhcr24 activates the PI3K/Akt/HKII pathway and protects against dilated cardiomyopathy in mice.
3β-Hydroxysterol-Delta24 reductase plays an important role in long bone growth by protecting chondrocytes from reactive oxygen species.
Seladin-1 is a novel lipopolysaccharide (LPS)-responsive gene and inhibits the tumour necrosis factor-alpha production and osteoclast formation in response to LPS.
Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate.
Hartwig C, Méndez GM, Bhattacharjee S, Vrailas-Mortimer AD, Zlatic SA, Freeman AAH, Gokhale A, Concilli M, Werner E, Sapp Savas C, Rudin-Rush S, Palmer L, Shearing N, Margewich L, McArthy J, Taylor S, Roberts B, Lupashin V, Polishchuk RS, Cox DN, Jorquera RA, Faundez V
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Jan 13;41(2):215-233
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021 Jan 13;41(2):215-233
Efferocytosis potentiates the expression of arachidonate 15-lipoxygenase (ALOX15) in alternatively activated human macrophages through LXR activation.
Snodgrass RG, Benatzy Y, Schmid T, Namgaladze D, Mainka M, Schebb NH, Lütjohann D, Brüne B
Cell death and differentiation 2021 Apr;28(4):1301-1316
Cell death and differentiation 2021 Apr;28(4):1301-1316
Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis.
Lu XY, Shi XJ, Hu A, Wang JQ, Ding Y, Jiang W, Sun M, Zhao X, Luo J, Qi W, Song BL
Nature 2020 Dec;588(7838):479-484
Nature 2020 Dec;588(7838):479-484
Dhcr24 activates the PI3K/Akt/HKII pathway and protects against dilated cardiomyopathy in mice.
Dong W, Guan FF, Zhang X, Gao S, Liu N, Chen W, Zhang LF, Lu D
Animal models and experimental medicine 2018 Mar;1(1):40-52
Animal models and experimental medicine 2018 Mar;1(1):40-52
3β-Hydroxysterol-Delta24 reductase plays an important role in long bone growth by protecting chondrocytes from reactive oxygen species.
Mirza R, Qiao S, Tateyama K, Miyamoto T, Xiuli L, Seo H
Journal of bone and mineral metabolism 2012 Mar;30(2):144-53
Journal of bone and mineral metabolism 2012 Mar;30(2):144-53
Seladin-1 is a novel lipopolysaccharide (LPS)-responsive gene and inhibits the tumour necrosis factor-alpha production and osteoclast formation in response to LPS.
Khuda II, Koide N, Noman AS, Dagvadorj J, Tumurkhuu G, Naiki Y, Komatsu T, Yoshida T, Yokochi T
Immunology 2010 Sep;131(1):59-66
Immunology 2010 Sep;131(1):59-66
Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate.
Legg RL, Tolman JR, Lovinger CT, Lephart ED, Setchell KD, Christensen MJ
Reproductive biology and endocrinology : RB&E 2008 Nov 24;6:57
Reproductive biology and endocrinology : RB&E 2008 Nov 24;6:57
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 10471-1-AP(DHCR24 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Seladin 1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Seladin 1. This antibody recognizes human,mouse,rat antigen. The Seladin 1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.