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- Product number
- GTX129859 - Provider product page
- Provider
- GeneTex
- Product name
- PCSK9 antibody
- Antibody type
- Polyclonal
- Reactivity
- Human
- Host
- Rabbit
Submitted references The Cholesterol-Modulating Effect of Methanol Extract of Pigeon Pea (Cajanus cajan (L.) Millsp.) Leaves on Regulating LDLR and PCSK9 Expression in HepG2 Cells.
Pinostrobin Inhibits Proprotein Convertase Subtilisin/Kexin-type 9 (PCSK9) Gene Expression through the Modulation of FoxO3a Protein in HepG2 Cells.
Xanthohumol Suppresses Mylip/Idol Gene Expression and Modulates LDLR Abundance and Activity in HepG2 Cells.
Tanshinone IIA Modulates Low Density Lipoprotein Uptake via Down-Regulation of PCSK9 Gene Expression in HepG2 Cells.
Hypocholesterolaemic Activity of Lupin Peptides: Investigation on the Crosstalk between Human Enterocytes and Hepatocytes Using a Co-Culture System Including Caco-2 and HepG2 Cells.
Chang HY, Wu JR, Gao WY, Lin HR, Chen PY, Chen CI, Wu MJ, Yen JH
Molecules (Basel, Switzerland) 2019 Jan 30;24(3)
Molecules (Basel, Switzerland) 2019 Jan 30;24(3)
Pinostrobin Inhibits Proprotein Convertase Subtilisin/Kexin-type 9 (PCSK9) Gene Expression through the Modulation of FoxO3a Protein in HepG2 Cells.
Gao WY, Chen PY, Chen SF, Wu MJ, Chang HY, Yen JH
Journal of agricultural and food chemistry 2018 Jun 20;66(24):6083-6093
Journal of agricultural and food chemistry 2018 Jun 20;66(24):6083-6093
Xanthohumol Suppresses Mylip/Idol Gene Expression and Modulates LDLR Abundance and Activity in HepG2 Cells.
Chen SF, Chen PY, Hsu HJ, Wu MJ, Yen JH
Journal of agricultural and food chemistry 2017 Sep 13;65(36):7908-7918
Journal of agricultural and food chemistry 2017 Sep 13;65(36):7908-7918
Tanshinone IIA Modulates Low Density Lipoprotein Uptake via Down-Regulation of PCSK9 Gene Expression in HepG2 Cells.
Chen HC, Chen PY, Wu MJ, Tai MH, Yen JH
PloS one 2016;11(9):e0162414
PloS one 2016;11(9):e0162414
Hypocholesterolaemic Activity of Lupin Peptides: Investigation on the Crosstalk between Human Enterocytes and Hepatocytes Using a Co-Culture System Including Caco-2 and HepG2 Cells.
Lammi C, Zanoni C, Ferruzza S, Ranaldi G, Sambuy Y, Arnoldi A
Nutrients 2016 Jul 22;8(7)
Nutrients 2016 Jul 22;8(7)
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- PCSK9 antibody detects PCSK9 protein by western blot analysis. Various whole cell extracts (30 ?g) were separated by 7.5 % SDS-PAGE, and blotted with PCSK9 antibody (GTX129859) diluted by 1:500
- Validation comment
- WB
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- PCSK9 antibody detects PCSK9 protein by western blot analysis. Various whole cell extracts (30 £gg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PCSK9 antibody (GTX129859) diluted at a dilution of 1:500.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Wild-type (WT) and PCSK9 knockout (KO) HeLa cell extracts (30 ?g) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PCSK9 antibody (GTX129859) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Wild-type (WT) and PCSK9 knockout (KO) HeLa cell extracts (30 ?g) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PCSK9 antibody (GTX129859) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
