AF1122

antibody from Novus Biologicals

Targeting: TACSTD2 EGP-1, GA733-1, M1S1, TROP2

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

AF1122

Provider

Novus Biologicals

Product name

Goat Polyclonal TROP-2 Antibody

Antibody type

Polyclonal

Description

Antigen Affinity-purified. Detects mouse TROP-2 in direct ELISAs and Western blots. In direct ELISAs, less than 30% cross-reactivity with recombinant human TROP-2 is observed.

Reactivity

Mouse

Host

Goat

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

References

Submitted references

Relief of tumor hypoxia unleashes the tumoricidal potential of neutrophils.

Mahiddine K, Blaisdell A, Ma S, Créquer-Grandhomme A, Lowell CA, Erlebacher A
The Journal of clinical investigation 2020 Jan 2;130(1):389-403

---

Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium.

Lynch TJ, Anderson PJ, Rotti PG, Tyler SR, Crooke AK, Choi SH, Montoro DT, Silverman CL, Shahin W, Zhao R, Jensen-Cody CW, Adamcakova-Dodd A, Evans TIA, Xie W, Zhang Y, Mou H, Herring BP, Thorne PS, Rajagopal J, Yeaman C, Parekh KR, Engelhardt JF
Cell stem cell 2018 May 3;22(5):653-667.e5

---

YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration.

Yui S, Azzolin L, Maimets M, Pedersen MT, Fordham RP, Hansen SL, Larsen HL, Guiu J, Alves MRP, Rundsten CF, Johansen JV, Li Y, Madsen CD, Nakamura T, Watanabe M, Nielsen OH, Schweiger PJ, Piccolo S, Jensen KB
Cell stem cell 2018 Jan 4;22(1):35-49.e7

---

Maternal Fat Feeding Augments Offspring Nephron Endowment in Mice.

Hokke S, Puelles VG, Armitage JA, Fong K, Bertram JF, Cullen-McEwen LA
PloS one 2016;11(8):e0161578

---

Pten Regulates Epithelial Cytodifferentiation during Prostate Development.

Lokody IB, Francis JC, Gardiner JR, Erler JT, Swain A
PloS one 2015;10(6):e0129470

---

Hepatocytes, rather than cholangiocytes, can be the major source of primitive ductules in the chronically injured mouse liver.

Sekiya S, Suzuki A
The American journal of pathology 2014 May;184(5):1468-78

---

Nrf2 enhances cholangiocyte expansion in Pten-deficient livers.

Taguchi K, Hirano I, Itoh T, Tanaka M, Miyajima A, Suzuki A, Motohashi H, Yamamoto M
Molecular and cellular biology 2014 Mar;34(5):900-13

---

Global quantification of tissue dynamics in the developing mouse kidney.

Short KM, Combes AN, Lefevre J, Ju AL, Georgas KM, Lamberton T, Cairncross O, Rumballe BA, McMahon AP, Hamilton NA, Smyth IM, Little MH
Developmental cell 2014 Apr 28;29(2):188-202

---

Identification of TROP2 (TACSTD2), an EpCAM-like molecule, as a specific marker for TGF-β1-dependent human epidermal Langerhans cells.

Eisenwort G, Jurkin J, Yasmin N, Bauer T, Gesslbauer B, Strobl H
The Journal of investigative dermatology 2011 Oct;131(10):2049-57

Immunohistochemistry

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

TROP-2 in Mouse Skin. TROP-2 in Mouse Skin.

Flow cytometry

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Detection of TROP-2 in mIMCD-3 Mouse Cell Line by Flow Cytometry. Detection of TROP-2 in mIMCD-3 Mouse Cell Line by Flow Cytometry.