Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
- Blocking/Neutralizing [1]
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Validation data
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- Product number
- AF4160 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal Plexin D1 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human Plexin D1 in direct ELISAs and Western blots.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Post-endocytic sorting of Plexin-D1 controls signal transduction and development of axonal and vascular circuits.
Chemorepellent Semaphorin 3E Negatively Regulates Neutrophil Migration In Vitro and In Vivo.
Semaphorin 3G Provides a Repulsive Guidance Cue to Lymphatic Endothelial Cells via Neuropilin-2/PlexinD1.
An image-based RNAi screen identifies SH3BP1 as a key effector of Semaphorin 3E-PlexinD1 signaling.
Dual role for Islet-1 in promoting striatonigral and repressing striatopallidal genetic programs to specify striatonigral cell identity.
Sema3E-Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in mice.
Burk K, Mire E, Bellon A, Hocine M, Guillot J, Moraes F, Yoshida Y, Simons M, Chauvet S, Mann F
Nature communications 2017 Feb 22;8:14508
Nature communications 2017 Feb 22;8:14508
Chemorepellent Semaphorin 3E Negatively Regulates Neutrophil Migration In Vitro and In Vivo.
Movassagh H, Saati A, Nandagopal S, Mohammed A, Tatari N, Shan L, Duke-Cohan JS, Fowke KR, Lin F, Gounni AS
Journal of immunology (Baltimore, Md. : 1950) 2017 Feb 1;198(3):1023-1033
Journal of immunology (Baltimore, Md. : 1950) 2017 Feb 1;198(3):1023-1033
Semaphorin 3G Provides a Repulsive Guidance Cue to Lymphatic Endothelial Cells via Neuropilin-2/PlexinD1.
Liu X, Uemura A, Fukushima Y, Yoshida Y, Hirashima M
Cell reports 2016 Nov 22;17(9):2299-2311
Cell reports 2016 Nov 22;17(9):2299-2311
An image-based RNAi screen identifies SH3BP1 as a key effector of Semaphorin 3E-PlexinD1 signaling.
Tata A, Stoppel DC, Hong S, Ben-Zvi A, Xie T, Gu C
The Journal of cell biology 2014 May 26;205(4):573-90
The Journal of cell biology 2014 May 26;205(4):573-90
Dual role for Islet-1 in promoting striatonigral and repressing striatopallidal genetic programs to specify striatonigral cell identity.
Lu KM, Evans SM, Hirano S, Liu FC
Proceedings of the National Academy of Sciences of the United States of America 2014 Jan 7;111(1):E168-77
Proceedings of the National Academy of Sciences of the United States of America 2014 Jan 7;111(1):E168-77
Sema3E-Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in mice.
Casazza A, Finisguerra V, Capparuccia L, Camperi A, Swiercz JM, Rizzolio S, Rolny C, Christensen C, Bertotti A, Sarotto I, Risio M, Trusolino L, Weitz J, Schneider M, Mazzone M, Comoglio PM, Tamagnone L
The Journal of clinical investigation 2010 Aug;120(8):2684-98
The Journal of clinical investigation 2010 Aug;120(8):2684-98
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human Plexin D1 by Western Blot. Detection of Human Plexin D1 by Western Blot.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Plexin D1 in Human Melanoma. Plexin D1 in Human Melanoma.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Plexin D1 in Human peripheral blood monocytes by Flow Cytometry. Detection of Plexin D1 in Human peripheral blood monocytes by Flow Cytometry.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Proliferation Inhibited by Semaphorin 3E and Neutralization by Human Plexin D1 Antibody. Proliferation Inhibited by Semaphorin 3E and Neutralization by Human Plexin D1 Antibody.