11-4036

antibody from ABEOMICS Inc.
Targeting: IL37 FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1F7
Provider product page for 11-4036

Antibody data

Product number
11-4036 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-IL-37 Antibody
Antibody type
Polyclonal
Description
IL-37 (Interleukin-37) is a member of IL-1 family and is primarily an anti-inflammatory cytokine, which reduces systemic and local inflammation. There are five different splice variants of IL-37 termed IL-37a-e, where Isoform IL-37b is the largest isoform. IL-37 has significant sequence similarity with IL-18 and highly expressed in inflammatory tissues, which inhibits the excessive inflammatory response. The expression is highly induced by several toll-like receptor (TLR) ligands and pro-inflammatory cytokines such as IL-1beta, TNF-alpha, IFN-gamma. IL-37 is a potent inhibitor of innate immunity by shifting the cytokine equilibrium away from excessive inflammation.
Reactivity
Human
Host
Rabbit
Antigen sequence
Full length recombinant IL-37 prote
in was used as the immunogen for th
is antibody.
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
IL37 protein structure - 11-4036 shown in red.