BS7893

antibody from Bioworld Technology, Inc
Targeting: ITGB3BP CENPR, HSU37139, NRIF3, TAP20
Provider product page for BS7893
Western blot
Immunohistochemistry

Antibody data

Product number
BS7893 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ITGB3BP polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human ITGB3BP.
Description
CENP-R (centromere protein R), also known as CENPR, ITGB3BP (Integrin ÉÇ3 binding protein), ÉÇ3-endonexin, NRIF3 (nuclear receptor-interacting factor 3) or TAP20, is a widely expressed protein that contains a DD1 or RepD1 domain and an LXXLL motif. Induced by estrogen, CENP-R is believed to function as a nuclear receptor coactivator. It also associates with the CENP-A-CAD complex which is involved in mitotic progression, the assembly of kinetochore proteins and chromosome segregation. A number of isoforms exist for CENP-R due to alternative splicing events. Isoform 1 localizes to the nucleus at the centromere; isoform 2, also known as EnL, En-L or long isoform, localizes to the nucleus; isoform 3, also known as EnS, En-S or short isoform, localizes predominantly to the nucleus but can also be found in the cytoplasm; and isoform 4 predominantly localizes to the cytoplasm. Isoform 3 of CENP-R binds to the cytoplasmic tail of Integrin ÉÇ3 and can activate Integrin Ï«IIb/ÉÇ3.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ITGB3BP protein structure - BS7893 shown in red.