Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Other assay [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- PA1-053 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Leptin Receptor Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- PA1-053 detects leptin (OB-R) from human, mouse, and rat tissues.
- Concentration
- 10 mg/mL
Submitted references Renal Metabolic Programming Is Linked to the Dynamic Regulation of a Leptin-Klf15 Axis and Akt/AMPKα Signaling in Male Offspring of Obese Dams.
Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance.
Leptin reduces pathology and improves memory in a transgenic mouse model of Alzheimer's disease.
ObRa and ObRe are differentially expressed in adipose tissue in aged food-restricted rats: effects on circulating soluble leptin receptor levels.
Estrogen and raloxifene modulate leptin and its receptor in hypothalamus and adipose tissue from ovariectomized rats.
Leptin distribution and metabolism in the pregnant rat: transplacental leptin passage increases in late gestation but is reduced by excess glucocorticoids.
Expression of leptin and its receptor in the murine ovary: possible role in the regulation of oocyte maturation.
Expression of leptin and its receptor in the murine ovary: possible role in the regulation of oocyte maturation.
Anti-leptin receptor antibody mimics the stimulation of lipolysis induced by leptin in isolated mouse fat pads.
Metabolic responses to leptin in obese db/db mice are strain dependent.
A leptin dose-response study in obese (ob/ob) and lean (+/?) mice.
Kasper P, Vohlen C, Dinger K, Mohr J, Hucklenbruch-Rother E, Janoschek R, Köth J, Matthes J, Appel S, Dötsch J, Alejandre Alcazar MA
Endocrinology 2017 Oct 1;158(10):3399-3415
Endocrinology 2017 Oct 1;158(10):3399-3415
Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance.
Bonda DJ, Stone JG, Torres SL, Siedlak SL, Perry G, Kryscio R, Jicha G, Casadesus G, Smith MA, Zhu X, Lee HG
Journal of neurochemistry 2014 Jan;128(1):162-72
Journal of neurochemistry 2014 Jan;128(1):162-72
Leptin reduces pathology and improves memory in a transgenic mouse model of Alzheimer's disease.
Greco SJ, Bryan KJ, Sarkar S, Zhu X, Smith MA, Ashford JW, Johnston JM, Tezapsidis N, Casadesus G
Journal of Alzheimer's disease : JAD 2010;19(4):1155-67
Journal of Alzheimer's disease : JAD 2010;19(4):1155-67
ObRa and ObRe are differentially expressed in adipose tissue in aged food-restricted rats: effects on circulating soluble leptin receptor levels.
Gallardo N, Arribas C, Villar M, Ros M, Carrascosa JM, Martínez C, Andrés A
Endocrinology 2005 Nov;146(11):4934-42
Endocrinology 2005 Nov;146(11):4934-42
Estrogen and raloxifene modulate leptin and its receptor in hypothalamus and adipose tissue from ovariectomized rats.
Meli R, Pacilio M, Raso GM, Esposito E, Coppola A, Nasti A, Di Carlo C, Nappi C, Di Carlo R
Endocrinology 2004 Jul;145(7):3115-21
Endocrinology 2004 Jul;145(7):3115-21
Leptin distribution and metabolism in the pregnant rat: transplacental leptin passage increases in late gestation but is reduced by excess glucocorticoids.
Smith JT, Waddell BJ
Endocrinology 2003 Jul;144(7):3024-30
Endocrinology 2003 Jul;144(7):3024-30
Expression of leptin and its receptor in the murine ovary: possible role in the regulation of oocyte maturation.
Ryan NK, Woodhouse CM, Van der Hoek KH, Gilchrist RB, Armstrong DT, Norman RJ
Biology of reproduction 2002 May;66(5):1548-54
Biology of reproduction 2002 May;66(5):1548-54
Expression of leptin and its receptor in the murine ovary: possible role in the regulation of oocyte maturation.
Ryan NK, Woodhouse CM, Van der Hoek KH, Gilchrist RB, Armstrong DT, Norman RJ
Biology of reproduction 2002 May;66(5):1548-54
Biology of reproduction 2002 May;66(5):1548-54
Anti-leptin receptor antibody mimics the stimulation of lipolysis induced by leptin in isolated mouse fat pads.
Kawaji N, Yoshida A, Motoyashiki T, Morita T, Ueki H
Journal of lipid research 2001 Oct;42(10):1671-7
Journal of lipid research 2001 Oct;42(10):1671-7
Metabolic responses to leptin in obese db/db mice are strain dependent.
Harris RB, Mitchell TD, Yan X, Simpson JS, Redmann SM Jr
American journal of physiology. Regulatory, integrative and comparative physiology 2001 Jul;281(1):R115-32
American journal of physiology. Regulatory, integrative and comparative physiology 2001 Jul;281(1):R115-32
A leptin dose-response study in obese (ob/ob) and lean (+/?) mice.
Harris RB, Zhou J, Redmann SM Jr, Smagin GN, Smith SR, Rodgers E, Zachwieja JJ
Endocrinology 1998 Jan;139(1):8-19
Endocrinology 1998 Jan;139(1):8-19
No comments: Submit comment
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot detection of both short and long forms of OB-R from mouse lung tissue extract using Product # PA1-053.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
