Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN955319 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Translin (TSN) (AA 116-146), (Middle Region) antibody
- Antibody type
- Polyclonal
- Antigen
- KLH conjugated synthetic peptide between 116-146 amino acids from the Central region of human TSN
- Description
- Protein A column followed by peptide affinity purification
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 116-146,Middle Region
- Vial size
- 0.4 mL
- Concentration
- 0.25 mg/mL
- Storage
- Store at 2 - 8°C for up to six months or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Dendritic trafficking of BDNF mRNA is mediated by translin and blocked by the G196A (Val66Met) mutation.
Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations.
GTP-induced conformational changes in translin: a comparison between human and Drosophila proteins.
Chiaruttini C, Vicario A, Li Z, Baj G, Braiuca P, Wu Y, Lee FS, Gardossi L, Baraban JM, Tongiorgi E
Proceedings of the National Academy of Sciences of the United States of America 2009 Sep 22;106(38):16481-6
Proceedings of the National Academy of Sciences of the United States of America 2009 Sep 22;106(38):16481-6
Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations.
Lasky-Su J, Neale BM, Franke B, Anney RJ, Zhou K, Maller JB, Vasquez AA, Chen W, Asherson P, Buitelaar J, Banaschewski T, Ebstein R, Gill M, Miranda A, Mulas F, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Sonuga-Barke E, Steinhausen HC, Taylor E, Daly M, Laird N, Lange C, Faraone SV
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008 Dec 5;147B(8):1345-54
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008 Dec 5;147B(8):1345-54
GTP-induced conformational changes in translin: a comparison between human and Drosophila proteins.
Sengupta K, Kamdar RP, D'Souza JS, Mustafi SM, Rao BJ
Biochemistry 2006 Jan 24;45(3):861-70
Biochemistry 2006 Jan 24;45(3):861-70
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- TSN Antibody (Center) (AP54375PU-N) western blot analysis in Hela cell line lysates (35 μg/lane). This demonstrates the TSN antibody detected the TSN protein (arrow).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- TSN Antibody (Center) (AP54375PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of TSN Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.