CABT-L1315

antibody from Creative Diagnostics

Targeting: GADD45A DDIT1, GADD45

Western blot (Recommended by provider)

Antibody Data

Product number

CABT-L1315

Provider

Creative Diagnostics

Product name

Rabbit Anti-Human GADD45A monoclonal antibody, clone E.92.F

Antibody type

Monoclonal

Description

GADD45 alpha, beta and gamma are an evolutionarily conserved, homologous family of nuclear proteins that function as stress sensors for cellular physiological and environmental damage. GADD45 proteins are required for the activation of the G2/M checkpoint induced by UV radiation or alkylating agents. GADD45-induced G2/M checkpoint is regulated through inactivation of Cdc2-cyclin B1 kinase. GADD45 forms a complex with p21 and Cdc2, and may serve as core for interaction with other cell cycle regulators.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

E.92.F

Storage

-20°C