BS7389

antibody from Bioworld Technology, Inc
Targeting: PRNP AltPrP, CD230, CJD, GSS, PRIP, PRP
Provider product page for BS7389
Western blot
Immunohistochemistry

Antibody data

Product number
BS7389 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PRNP polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PRNP.
Description
The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PRNP protein structure - BS7389 shown in red.