Ab126068

antibody from Aladdin Scientific Corporation

Targeting: RPS6KA2 HU-2, RSK3

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

Ab126068

Provider

Aladdin Scientific Corporation

Product name

Recombinant RSK3 Antibody

Antibody type

Recombinant

Description

Rabbit anti Human RSK3 Antibody, Recombinant (R05-5E4), could be used for WB, IHC, ICC, IF and so on.Application:WB: 1/500 - 1/1000IHC: 1/50-1/100ICC/IF: 1/50-1/200Protein FunctionSerine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumor suppressor in epithelial ovarian cancer cells.Post-translationalActivated by phosphorylation at Ser-218 by PDPK1. Autophosphorylated on Ser-377, as part of the activation process. May be phosphorylated at Thr-356 and Ser-360 by MAPK1/ERK2 and MAPK3/ERK1. N-terminal myristoylation results in an activated kinase in the absence of added growth factors.

Reactivity

Human, Mouse, Rat, Hamster

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

AA 343-362


Antibody clone number

R05-5E4

Vial size

100μl,10μl,1ml,50μl

Concentration

0,6 mg/ml

Storage

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.