Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [2]
- ELISA [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- H00002992-M07 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00002992-M07, RRID:AB_539428
- Product name
- Mouse Monoclonal Glycogenin 1 Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. GYG1 - glycogenin 1
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Lack of Glycogenin Causes Glycogen Accumulation and Muscle Function Impairment.
Cardiomyopathy as presenting sign of glycogenin-1 deficiency-report of three cases and review of the literature.
Clinical heterogeneity and phenotype/genotype findings in 5 families with GYG1 deficiency.
Start codon mutation of GYG1 causing late-onset polyglucosan body myopathy with nemaline rods.
LC-MS/MS characterization of combined glycogenin-1 and glycogenin-2 enzymatic activities reveals their self-glucosylation preferences.
A new muscle glycogen storage disease associated with glycogenin-1 deficiency.
Dysregulation of multiple facets of glycogen metabolism in a murine model of Pompe disease.
Molecular pathogenesis of a new glycogenosis caused by a glycogenin-1 mutation.
Liver-specific inducible nitric-oxide synthase expression is sufficient to cause hepatic insulin resistance and mild hyperglycemia in mice.
Testoni G, Duran J, García-Rocha M, Vilaplana F, Serrano AL, Sebastián D, López-Soldado I, Sullivan MA, Slebe F, Vilaseca M, Muñoz-Cánoves P, Guinovart JJ
Cell metabolism 2017 Jul 5;26(1):256-266.e4
Cell metabolism 2017 Jul 5;26(1):256-266.e4
Cardiomyopathy as presenting sign of glycogenin-1 deficiency-report of three cases and review of the literature.
Hedberg-Oldfors C, Glamuzina E, Ruygrok P, Anderson LJ, Elliott P, Watkinson O, Occleshaw C, Abernathy M, Turner C, Kingston N, Murphy E, Oldfors A
Journal of inherited metabolic disease 2017 Jan;40(1):139-149
Journal of inherited metabolic disease 2017 Jan;40(1):139-149
Clinical heterogeneity and phenotype/genotype findings in 5 families with GYG1 deficiency.
Ben Yaou R, Hubert A, Nelson I, Dahlqvist JR, Gaist D, Streichenberger N, Beuvin M, Krahn M, Petiot P, Parisot F, Michel F, Malfatti E, Romero N, Carlier RY, Eymard B, Labrune P, Duno M, Krag T, Cerino M, Bartoli M, Bonne G, Vissing J, Laforet P, Petit FM
Neurology. Genetics 2017 Dec;3(6):e208
Neurology. Genetics 2017 Dec;3(6):e208
Start codon mutation of GYG1 causing late-onset polyglucosan body myopathy with nemaline rods.
Tasca G, Fattori F, Monforte M, Hedberg-Oldfors C, Sabatelli M, Udd B, Boldrini R, Bertini E, Ricci E, Oldfors A
Journal of neurology 2016 Oct;263(10):2133-5
Journal of neurology 2016 Oct;263(10):2133-5
LC-MS/MS characterization of combined glycogenin-1 and glycogenin-2 enzymatic activities reveals their self-glucosylation preferences.
Nilsson J, Halim A, Larsson E, Moslemi AR, Oldfors A, Larson G, Nilsson J
Biochimica et biophysica acta 2014 Feb;1844(2):398-405
Biochimica et biophysica acta 2014 Feb;1844(2):398-405
A new muscle glycogen storage disease associated with glycogenin-1 deficiency.
Malfatti E, Nilsson J, Hedberg-Oldfors C, Hernandez-Lain A, Michel F, Dominguez-Gonzalez C, Viennet G, Akman HO, Kornblum C, Van den Bergh P, Romero NB, Engel AG, DiMauro S, Oldfors A
Annals of neurology 2014 Dec;76(6):891-8
Annals of neurology 2014 Dec;76(6):891-8
Dysregulation of multiple facets of glycogen metabolism in a murine model of Pompe disease.
Taylor KM, Meyers E, Phipps M, Kishnani PS, Cheng SH, Scheule RK, Moreland RJ
PloS one 2013;8(2):e56181
PloS one 2013;8(2):e56181
Molecular pathogenesis of a new glycogenosis caused by a glycogenin-1 mutation.
Nilsson J, Halim A, Moslemi AR, Pedersen A, Nilsson J, Larson G, Oldfors A
Biochimica et biophysica acta 2012 Apr;1822(4):493-9
Biochimica et biophysica acta 2012 Apr;1822(4):493-9
Liver-specific inducible nitric-oxide synthase expression is sufficient to cause hepatic insulin resistance and mild hyperglycemia in mice.
Shinozaki S, Choi CS, Shimizu N, Yamada M, Kim M, Zhang T, Shiota G, Dong HH, Kim YB, Kaneki M
The Journal of biological chemistry 2011 Oct 7;286(40):34959-75
The Journal of biological chemistry 2011 Oct 7;286(40):34959-75
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Glycogenin 1 Antibody (3B5) [H00002992-M07] - Analysis of GYG1 expression in transfected 293T cell line by GYG1 monoclonal antibody (M07), clone 3B5. Lane 1: GYG1 transfected lysatE (37.5 KDa). Lane 2: Non-transfected lysate.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Glycogenin 1 Antibody (3B5) [H00002992-M07] - Analysis of GYG1 expression in HepG2 (Cat # L019V1).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- ELISA: Glycogenin 1 Antibody (3B5) [H00002992-M07] - Detection limit for recombinant GST tagged GYG1 is approximately 0.03ng/ml as a capture antibody.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Glycogenin 1 Antibody (3B5) [H00002992-M07] - Analysis of monoclonal antibody to GYG1 on formalin-fixed paraffin-embedded human testis. Antibody concentration 3 ug/ml