RAP2B

This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated. [provided by RefSeq, Jul 2008]

Description

RAP2B, member of RAS oncogene family

Tissue specificity

Low tissue specificity

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

3 (153162226 - 153170627)

Ensembl ID

ENSG00000181467  (ver. 103.38)

Orthologs

Mouse Rap2b: ENSMUSG00000036894

UniProt

P61225

neXtProt

NX_P61225

Human splice variants
Mouse splice variants

Protein structure