BS7904

antibody from Bioworld Technology, Inc
Targeting: TNFSF13B BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20
Provider product page for BS7904
Western blot
Immunohistochemistry

Antibody data

Product number
BS7904 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TNFSF13B polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human TNFSF13B.
Description
TNF cytokine family member TALL-1 (also designated BAFF, THANK and BLyS), is a type II membrane protein that shares characteristics with other members of the tumor necrosis factor (TNF) cytokine family. TALL-1 is expressed abun-dantly in peripheral blood leukocytes, monocytes and macrophages. TALL-1 is critically involved in the regulation of infections, inflammation, autoimmune diseases and tissue homeostasis. TALL-1 is a potent B cell stimulatory factor which is functionally involved in B cell proliferation and may be a primary mediator in B cell-associated autoimmune diseases. The C-terminal extracellular domain has b jelly roll topography and is important in ligand trimerization. The binding of the ligand to its respective receptor induces oligomerization, initiating downstream signaling events. Intrinsic to oligomerization is the formation of the receptor binding site at the junction between neighboring subunits, creating a multivalent ligand.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TNFSF13B protein structure - BS7904 shown in red.