ABIN500310
antibody from antibodies-online
Targeting: NLRP1
CARD7, CLR17.1, DEFCAP, DKFZp586O1822, KIAA0926, NAC, NALP1, SLEV1, VAMAS1
Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- ABIN500310 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-NLR Family, Pyrin Domain Containing 1 (NLRP1) antibody
- Antibody type
- Polyclonal
- Antigen
- NALP1 antibody was raised against a peptide corresponding to 13 amino acids near thecarboxy-terminus of human NALP1.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing. Shelf life: one year from despatch.
Submitted references NALP1 is a transcriptional target for cAMP-response-element-binding protein (CREB) in myeloid leukaemia cells.
NALPs: a novel protein family involved in inflammation.
A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis.
Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins.
Sanz C, Calasanz MJ, Andreu E, Richard C, Prosper F, Fernandez-Luna JL
The Biochemical journal 2004 Dec 1;384(Pt 2):281-6
The Biochemical journal 2004 Dec 1;384(Pt 2):281-6
NALPs: a novel protein family involved in inflammation.
Tschopp J, Martinon F, Burns K
Nature reviews. Molecular cell biology 2003 Feb;4(2):95-104
Nature reviews. Molecular cell biology 2003 Feb;4(2):95-104
A novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosis.
Chu ZL, Pio F, Xie Z, Welsh K, Krajewska M, Krajewski S, Godzik A, Reed JC
The Journal of biological chemistry 2001 Mar 23;276(12):9239-45
The Journal of biological chemistry 2001 Mar 23;276(12):9239-45
Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins.
Hlaing T, Guo RF, Dilley KA, Loussia JM, Morrish TA, Shi MM, Vincenz C, Ward PA
The Journal of biological chemistry 2001 Mar 23;276(12):9230-8
The Journal of biological chemistry 2001 Mar 23;276(12):9230-8
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of NALP1 in U937 cell lysate with AP30576PU-N at (A) 1, (B) 2 and (C) 4 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry of NALP1 in K562 cells with AP30576PU-N at 10 ?g/ml.