Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- ABIN1882062 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL) (Center), (AA 357-387) antibody
- Antibody type
- Polyclonal
- Antigen
- This AGL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 357-387 amino acids from the Central region of human AGL.
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- Center,AA 357-387
- Antibody clone number
- RB4976
- Vial size
- 400 μL
- Concentration
- 2 mg/mL
Submitted references Muscle glycogen remodeling and glycogen phosphate metabolism following exhaustive exercise of wild type and laforin knockout mice.
Genetic depletion of the malin E3 ubiquitin ligase in mice leads to lafora bodies and the accumulation of insoluble laforin.
Fast-twitch sarcomeric and glycolytic enzyme protein loss in inclusion body myositis.
Abnormal metabolism of glycogen phosphate as a cause for Lafora disease.
A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease.
Molecular cloning and nucleotide sequence of cDNA encoding human muscle glycogen debranching enzyme.
T cell receptor usage by HLA-DQw8-specific T cell clones.
Irimia JM, Tagliabracci VS, Meyer CM, Segvich DM, DePaoli-Roach AA, Roach PJ
The Journal of biological chemistry 2015 Sep 11;290(37):22686-98
The Journal of biological chemistry 2015 Sep 11;290(37):22686-98
Genetic depletion of the malin E3 ubiquitin ligase in mice leads to lafora bodies and the accumulation of insoluble laforin.
DePaoli-Roach AA, Tagliabracci VS, Segvich DM, Meyer CM, Irimia JM, Roach PJ
The Journal of biological chemistry 2010 Aug 13;285(33):25372-81
The Journal of biological chemistry 2010 Aug 13;285(33):25372-81
Fast-twitch sarcomeric and glycolytic enzyme protein loss in inclusion body myositis.
Parker KC, Kong SW, Walsh RJ, Bch, Salajegheh M, Moghadaszadeh B, Amato AA, Nazareno R, Lin YY, Krastins B, Sarracino DA, Beggs AH, Pinkus JL, Greenberg SA
Muscle & nerve 2009 Jun;39(6):739-53
Muscle & nerve 2009 Jun;39(6):739-53
Abnormal metabolism of glycogen phosphate as a cause for Lafora disease.
Tagliabracci VS, Girard JM, Segvich D, Meyer C, Turnbull J, Zhao X, Minassian BA, Depaoli-Roach AA, Roach PJ
The Journal of biological chemistry 2008 Dec 5;283(49):33816-25
The Journal of biological chemistry 2008 Dec 5;283(49):33816-25
A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease.
Cheng A, Zhang M, Gentry MS, Worby CA, Dixon JE, Saltiel AR
Genes & development 2007 Oct 1;21(19):2399-409
Genes & development 2007 Oct 1;21(19):2399-409
Molecular cloning and nucleotide sequence of cDNA encoding human muscle glycogen debranching enzyme.
Yang BZ, Ding JH, Enghild JJ, Bao Y, Chen YT
The Journal of biological chemistry 1992 May 5;267(13):9294-9
The Journal of biological chemistry 1992 May 5;267(13):9294-9
T cell receptor usage by HLA-DQw8-specific T cell clones.
Hansen T, Lundin KE, Markussen G, Thorsby E
International immunology 1992 Aug;4(8):931-4
International immunology 1992 Aug;4(8):931-4
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of hAGL-C371 (ABIN1882062) in K562 cell line lysates (35 μg/lane). AGL (arrow) was detected using the purified Pab.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of hAGL-C371 (ABIN1882062) in K562 cell line lysates (35 μg/lane). AGL (arrow) was detected using the purified Pab.