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- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 17069-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17069-1-AP, RRID:AB_2262009
- Product name
- EIF5A1/EIF5A2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated EIF5A1/EIF5A2 antibody (Cat. #17069-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.
Knockdown of EIF5A2 inhibits the malignant potential of non-small cell lung cancer cells.
EIF5A2 is a novel chemoresistance gene in breast cancer.
Cisplatin sensitivity is enhanced in non-small cell lung cancer cells by regulating epithelial-mesenchymal transition through inhibition of eukaryotic translation initiation factor 5A2.
Down-regulation of eIF5A-2 prevents epithelial-mesenchymal transition in non-small-cell lung cancer cells.
Novel functional MAR elements of double minute chromosomes in human ovarian cells capable of enhancing gene expression.
Ma D, Zheng B, Liu HL, Zhao YB, Liu X, Zhang XH, Li Q, Shi WB, Suzuki T, Wen JK
PLoS biology 2020 Aug;18(8):e3000808
PLoS biology 2020 Aug;18(8):e3000808
Knockdown of EIF5A2 inhibits the malignant potential of non-small cell lung cancer cells.
Chen C, Zhang B, Wu S, Song Y, Li J
Oncology letters 2018 Apr;15(4):4541-4549
Oncology letters 2018 Apr;15(4):4541-4549
EIF5A2 is a novel chemoresistance gene in breast cancer.
Liu Y, Du F, Chen W, Yao M, Lv K, Fu P
Breast cancer (Tokyo, Japan) 2015 Nov;22(6):602-7
Breast cancer (Tokyo, Japan) 2015 Nov;22(6):602-7
Cisplatin sensitivity is enhanced in non-small cell lung cancer cells by regulating epithelial-mesenchymal transition through inhibition of eukaryotic translation initiation factor 5A2.
Xu G, Yu H, Shi X, Sun L, Zhou Q, Zheng D, Shi H, Li N, Zhang X, Shao G
BMC pulmonary medicine 2014 Nov 7;14:174
BMC pulmonary medicine 2014 Nov 7;14:174
Down-regulation of eIF5A-2 prevents epithelial-mesenchymal transition in non-small-cell lung cancer cells.
Xu GD, Shi XB, Sun LB, Zhou QY, Zheng DW, Shi HS, Che YL, Wang ZS, Shao GF
Journal of Zhejiang University. Science. B 2013 Jun;14(6):460-7
Journal of Zhejiang University. Science. B 2013 Jun;14(6):460-7
Novel functional MAR elements of double minute chromosomes in human ovarian cells capable of enhancing gene expression.
Jin Y, Liu Z, Cao W, Ma X, Fan Y, Yu Y, Bai J, Chen F, Rosales J, Lee KY, Fu S
PloS one 2012;7(2):e30419
PloS one 2012;7(2):e30419
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 17069-1-AP(EIF5A2 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 17069-1-AP(EIF5A2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The EIF5A2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human EIF5A2. This antibody recognizes human, mouse, rat antigen. The EIF5A2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
