Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- NBP1-71775 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-71775, RRID:AB_11007496
- Product name
- Mouse Monoclonal Mitofusin 1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice.
Protective effect of exercise training against the progression of Alzheimer's disease in 3xTg-AD mice.
Alterations of proteome, mitochondrial dynamic and autophagy in the hypothalamus during activity-based anorexia.
MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells.
AD-linked, toxic NH2 human tau affects the quality control of mitochondria in neurons.
Mitochondrial toxic effects of Aβ through mitofusins in the early pathogenesis of Alzheimer's disease.
Myocardial contractile dysfunction is associated with impaired mitochondrial function and dynamics in type 2 diabetic but not in obese patients.
Mitochondrial dynamics associated with oxygen-glucose deprivation in rat primary neuronal cultures.
Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease.
IL-6 regulation on skeletal muscle mitochondrial remodeling during cancer cachexia in the ApcMin/+ mouse.
Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice.
Li T, Li K, Zhang S, Wang Y, Xu Y, Cronin SJF, Sun Y, Zhang Y, Xie C, Rodriguez J, Zhou K, Hagberg H, Mallard C, Wang X, Penninger JM, Kroemer G, Blomgren K, Zhu C
Cell death & disease 2020 Jan 30;11(1):77
Cell death & disease 2020 Jan 30;11(1):77
Protective effect of exercise training against the progression of Alzheimer's disease in 3xTg-AD mice.
Kim D, Cho J, Kang H
Behavioural brain research 2019 Nov 18;374:112105
Behavioural brain research 2019 Nov 18;374:112105
Alterations of proteome, mitochondrial dynamic and autophagy in the hypothalamus during activity-based anorexia.
Nobis S, Goichon A, Achamrah N, Guérin C, Azhar S, Chan P, Morin A, Bôle-Feysot C, do Rego JC, Vaudry D, Déchelotte P, Belmonte L, Coëffier M
Scientific reports 2018 May 8;8(1):7233
Scientific reports 2018 May 8;8(1):7233
MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells.
Bahat A, Goldman A, Zaltsman Y, Khan DH, Halperin C, Amzallag E, Krupalnik V, Mullokandov M, Silberman A, Erez A, Schimmer AD, Hanna JH, Gross A
Nature communications 2018 Dec 3;9(1):5132
Nature communications 2018 Dec 3;9(1):5132
AD-linked, toxic NH2 human tau affects the quality control of mitochondria in neurons.
Amadoro G, Corsetti V, Florenzano F, Atlante A, Ciotti MT, Mongiardi MP, Bussani R, Nicolin V, Nori SL, Campanella M, Calissano P
Neurobiology of disease 2014 Feb;62:489-507
Neurobiology of disease 2014 Feb;62:489-507
Mitochondrial toxic effects of Aβ through mitofusins in the early pathogenesis of Alzheimer's disease.
Wu Z, Zhu Y, Cao X, Sun S, Zhao B
Molecular neurobiology 2014 Dec;50(3):986-96
Molecular neurobiology 2014 Dec;50(3):986-96
Myocardial contractile dysfunction is associated with impaired mitochondrial function and dynamics in type 2 diabetic but not in obese patients.
Montaigne D, Marechal X, Coisne A, Debry N, Modine T, Fayad G, Potelle C, El Arid JM, Mouton S, Sebti Y, Duez H, Preau S, Remy-Jouet I, Zerimech F, Koussa M, Richard V, Neviere R, Edme JL, Lefebvre P, Staels B
Circulation 2014 Aug 12;130(7):554-64
Circulation 2014 Aug 12;130(7):554-64
Mitochondrial dynamics associated with oxygen-glucose deprivation in rat primary neuronal cultures.
Wappler EA, Institoris A, Dutta S, Katakam PV, Busija DW
PloS one 2013;8(5):e63206
PloS one 2013;8(5):e63206
Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease.
Trushina E, Nemutlu E, Zhang S, Christensen T, Camp J, Mesa J, Siddiqui A, Tamura Y, Sesaki H, Wengenack TM, Dzeja PP, Poduslo JF
PloS one 2012;7(2):e32737
PloS one 2012;7(2):e32737
IL-6 regulation on skeletal muscle mitochondrial remodeling during cancer cachexia in the ApcMin/+ mouse.
White JP, Puppa MJ, Sato S, Gao S, Price RL, Baynes JW, Kostek MC, Matesic LE, Carson JA
Skeletal muscle 2012 Jul 6;2:14
Skeletal muscle 2012 Jul 6;2:14
Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice.
Xu YF, Gendron TF, Zhang YJ, Lin WL, D'Alton S, Sheng H, Casey MC, Tong J, Knight J, Yu X, Rademakers R, Boylan K, Hutton M, McGowan E, Dickson DW, Lewis J, Petrucelli L
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Aug 11;30(32):10851-9
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Aug 11;30(32):10851-9
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Mitofusin 1 Antibody (11E9-1H12) [NBP1-71775] - Analysis of Mitofusin-1 expression in (1) MEF wild-type and (2) MEF Mitofusin-1-null whole cell lysates using NBP1-71775.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Mitofusin 1 Antibody (11E9-1H12) [NBP1-71775] - Analysis of Mitofusin-1 in mouse liver.