Antibody data
- Antibody Data
- Antigen structure
- References [38]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 14712-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14712-1-AP, RRID:AB_2160973
- Product name
- ERp72 antibody
- Antibody type
- Polyclonal
- Description
- ERp72 antibody (Cat. #14712-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Anticancer effect of hUC-MSC-derived exosome-mediated delivery of PMO-miR-146b-5p in colorectal cancer.
Expression of SARS-CoV-2 Nonstructural Proteins 3 and 4 Can Tune the Unfolded Protein Response in Cell Culture.
Protein disulfide isomerase family member 4 promotes triple-negative breast cancer tumorigenesis and radiotherapy resistance through JNK pathway.
Conditional hepatocyte ablation of PDIA1 uncovers indispensable roles in both APOB and MTTP folding to support VLDL secretion.
Investigation of Glycosylphosphatidylinositol (GPI)-Plasma Membrane Interaction in Live Cells and the Influence of GPI Glycan Structure on the Interaction.
PDIA4 Is a Host Factor Important for Lymphocytic Choriomeningitis Virus Infection.
Glucose-mediated N-glycosylation of RPTPα affects its subcellular localization and Src activation.
Protein disulfide-isomerase A4 confers glioblastoma angiogenesis promotion capacity and resistance to anti-angiogenic therapy.
PDIA4 confers resistance to ferroptosis via induction of ATF4/SLC7A11 in renal cell carcinoma.
SARS-CoV-2 Nonstructural Proteins 3 and 4 tune the Unfolded Protein Response.
SINE-VNTR-Alu retrotransposon insertion as a novel mutational event underlying Glanzmann thrombasthenia.
The role of lysosomes as intermediates in betacoronavirus PHEV egress from nerve cells.
Assembly-dependent Structure Formation Shapes Human Interleukin-23 versus Interleukin-12 Secretion.
Divergent Proteome Reactivity Influences Arm-Selective Activation of the Unfolded Protein Response by Pharmacological Endoplasmic Reticulum Proteostasis Regulators.
High expression of PDIA4 promotes malignant cell behavior and predicts reduced survival in cervical cancer.
ATF6 Activation Reduces Amyloidogenic Transthyretin Secretion through Increased Interactions with Endoplasmic Reticulum Proteostasis Factors.
A comprehensive set of ER protein disulfide isomerase family members supports the biogenesis of proinflammatory interleukin 12 family cytokines.
Albumin (ALB) and protein disulfide isomerase family A member 4 (PDIA4) are novel markers to predict sperm freezability of Erhualian boar.
Long noncoding RNA Gm2694 drives depressive-like behaviors in male mice by interacting with GRP78 to disrupt endoplasmic reticulum homeostasis.
miRNA-mRNA Regulatory Network Reveals miRNAs in HCT116 in Response to Folic Acid Deficiency via Regulating Vital Genes of Endoplasmic Reticulum Stress Pathway.
Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs.
Thyroglobulin Interactome Profiling Defines Altered Proteostasis Topology Associated With Thyroid Dyshormonogenesis.
Comparative host interactomes of the SARS-CoV-2 nonstructural protein 3 and human coronavirus homologs.
A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes.
Identification and detection of mecciRNAs.
Identification of mecciRNAs and their roles in the mitochondrial entry of proteins.
Comparative multiplexed interactomics of SARS-CoV-2 and homologous coronavirus non-structural proteins identifies unique and shared host-cell dependencies.
Comparative Multiplexed Interactomics of SARS-CoV-2 and Homologous Coronavirus Nonstructural Proteins Identifies Unique and Shared Host-Cell Dependencies.
PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity.
Quantitative Interactome Proteomics Reveals a Molecular Basis for ATF6-Dependent Regulation of a Destabilized Amyloidogenic Protein.
N-Glycosylation is required for FDNC5 stabilization and irisin secretion.
Expression of protein disulfide isomerase family members correlates with tumor progression and patient survival in ovarian cancer.
Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation.
Mapping wild-type and R345W fibulin-3 intracellular interactomes.
Identification and characterization of an endoplasmic reticulum localization motif.
MicroRNA directly enhances mitochondrial translation during muscle differentiation.
Inhibition by imatinib of expression of O-glycan-related glycosyltransferases and tumor-associated carbohydrate antigens in the K562 human leukemia cell line.
Receptor-like protein-tyrosine phosphatase α enhances cell surface expression of neural adhesion molecule NB-3.
Yu S, Liao R, Bai L, Guo M, Zhang Y, Zhang Y, Yang Q, Song Y, Li Z, Meng Q, Wang S, Huang X
Drug delivery and translational research 2024 May;14(5):1352-1369
Drug delivery and translational research 2024 May;14(5):1352-1369
Expression of SARS-CoV-2 Nonstructural Proteins 3 and 4 Can Tune the Unfolded Protein Response in Cell Culture.
Davies JP, Sivadas A, Keller KR, Roman BK, Wojcikiewicz RJH, Plate L
Journal of proteome research 2024 Jan 5;23(1):356-367
Journal of proteome research 2024 Jan 5;23(1):356-367
Protein disulfide isomerase family member 4 promotes triple-negative breast cancer tumorigenesis and radiotherapy resistance through JNK pathway.
Tao J, Xue C, Cao M, Ye J, Sun Y, Chen H, Guan Y, Zhang W, Zhang W, Yao Y
Breast cancer research : BCR 2024 Jan 2;26(1):1
Breast cancer research : BCR 2024 Jan 2;26(1):1
Conditional hepatocyte ablation of PDIA1 uncovers indispensable roles in both APOB and MTTP folding to support VLDL secretion.
Chen Z, Wang S, Pottekat A, Duffey A, Jang I, Chang BH, Cho J, Finck BN, Davidson NO, Kaufman RJ
Molecular metabolism 2024 Feb;80:101874
Molecular metabolism 2024 Feb;80:101874
Investigation of Glycosylphosphatidylinositol (GPI)-Plasma Membrane Interaction in Live Cells and the Influence of GPI Glycan Structure on the Interaction.
Kundu S, Jaiswal M, Babu Mullapudi V, Guo J, Kamat M, Basso KB, Guo Z
Chemistry (Weinheim an der Bergstrasse, Germany) 2024 Feb 7;30(8):e202303047
Chemistry (Weinheim an der Bergstrasse, Germany) 2024 Feb 7;30(8):e202303047
PDIA4 Is a Host Factor Important for Lymphocytic Choriomeningitis Virus Infection.
Xu M, Xu H, Wan W, Jian X, Jin R, Wang L, Wang J, Xiao G, Zhang L, Chen H, Wen Y
Viruses 2023 Nov 29;15(12)
Viruses 2023 Nov 29;15(12)
Glucose-mediated N-glycosylation of RPTPα affects its subcellular localization and Src activation.
Fang J, Zhang Y, Huang C, Lu R, Yu J, Chen R, Wang Y, Zhao X, Yu J, Huang J
Oncogene 2023 Mar;42(14):1058-1071
Oncogene 2023 Mar;42(14):1058-1071
Protein disulfide-isomerase A4 confers glioblastoma angiogenesis promotion capacity and resistance to anti-angiogenic therapy.
Tu Z, Wang C, Hu Q, Tao C, Fang Z, Lin L, Lei K, Luo M, Sheng Y, Long X, Li J, Wu L, Huang K, Zhu X
Journal of experimental & clinical cancer research : CR 2023 Mar 30;42(1):77
Journal of experimental & clinical cancer research : CR 2023 Mar 30;42(1):77
PDIA4 confers resistance to ferroptosis via induction of ATF4/SLC7A11 in renal cell carcinoma.
Kang L, Wang D, Shen T, Liu X, Dai B, Zhou D, Shen H, Gong J, Li G, Hu Y, Wang P, Mi X, Zhang Y, Tan X
Cell death & disease 2023 Mar 11;14(3):193
Cell death & disease 2023 Mar 11;14(3):193
SARS-CoV-2 Nonstructural Proteins 3 and 4 tune the Unfolded Protein Response.
Davies JP, Sivadas A, Keller KR, Wojcikiewicz RJH, Plate L
bioRxiv : the preprint server for biology 2023 Jun 12;
bioRxiv : the preprint server for biology 2023 Jun 12;
SINE-VNTR-Alu retrotransposon insertion as a novel mutational event underlying Glanzmann thrombasthenia.
Zhang J, Tang J, Li G, Li N, Wang J, Yao R, Yu T
Journal of thrombosis and haemostasis : JTH 2023 Dec;21(12):3597-3607
Journal of thrombosis and haemostasis : JTH 2023 Dec;21(12):3597-3607
The role of lysosomes as intermediates in betacoronavirus PHEV egress from nerve cells.
Wang Z, He W, Li C, Chen Y, Li Z, Jiao Y, Zhang J, Shi J, Wang G, Guan J, Zhao K, Song D, Gao F, Lan Y
Journal of virology 2023 Dec 21;97(12):e0133823
Journal of virology 2023 Dec 21;97(12):e0133823
Assembly-dependent Structure Formation Shapes Human Interleukin-23 versus Interleukin-12 Secretion.
Aschenbrenner I, Siebenmorgen T, Lopez A, Parr M, Ruckgaber P, Kerle A, Rührnößl F, Catici D, Haslbeck M, Frishman D, Sattler M, Zacharias M, Feige MJ
Journal of molecular biology 2023 Dec 1;435(23):168300
Journal of molecular biology 2023 Dec 1;435(23):168300
Divergent Proteome Reactivity Influences Arm-Selective Activation of the Unfolded Protein Response by Pharmacological Endoplasmic Reticulum Proteostasis Regulators.
Kline GM, Paxman RJ, Lin CY, Madrazo N, Yoon L, Grandjean JMD, Lee K, Nugroho K, Powers ET, Wiseman RL, Kelly JW
ACS chemical biology 2023 Aug 18;18(8):1719-1729
ACS chemical biology 2023 Aug 18;18(8):1719-1729
High expression of PDIA4 promotes malignant cell behavior and predicts reduced survival in cervical cancer.
Xing F, Song Z, Cheng Z
Oncology reports 2022 Oct;48(4)
Oncology reports 2022 Oct;48(4)
ATF6 Activation Reduces Amyloidogenic Transthyretin Secretion through Increased Interactions with Endoplasmic Reticulum Proteostasis Factors.
Mesgarzadeh JS, Romine IC, Smith-Cohen EM, Grandjean JMD, Kelly JW, Genereux JC, Wiseman RL
Cells 2022 May 17;11(10)
Cells 2022 May 17;11(10)
A comprehensive set of ER protein disulfide isomerase family members supports the biogenesis of proinflammatory interleukin 12 family cytokines.
Mideksa YG, Aschenbrenner I, Fux A, Kaylani D, Weiß CAM, Nguyen TA, Bach NC, Lang K, Sieber SA, Feige MJ
The Journal of biological chemistry 2022 Dec;298(12):102677
The Journal of biological chemistry 2022 Dec;298(12):102677
Albumin (ALB) and protein disulfide isomerase family A member 4 (PDIA4) are novel markers to predict sperm freezability of Erhualian boar.
Tong S, Yin C, Ge Y, Ren Z, Tao J, Liu Y
Cryobiology 2022 Dec;109:37-43
Cryobiology 2022 Dec;109:37-43
Long noncoding RNA Gm2694 drives depressive-like behaviors in male mice by interacting with GRP78 to disrupt endoplasmic reticulum homeostasis.
Chen HS, Wang J, Li HH, Wang X, Zhang SQ, Deng T, Li YK, Zou RS, Wang HJ, Zhu R, Xie WL, Zhao G, Wang F, Chen JG
Science advances 2022 Dec 2;8(48):eabn2496
Science advances 2022 Dec 2;8(48):eabn2496
miRNA-mRNA Regulatory Network Reveals miRNAs in HCT116 in Response to Folic Acid Deficiency via Regulating Vital Genes of Endoplasmic Reticulum Stress Pathway.
Lu L, Zhao H, Liu J, Zhang Y, Wang X
BioMed research international 2021;2021:6650181
BioMed research international 2021;2021:6650181
Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs.
Almasy KM, Davies JP, Plate L
Molecular & cellular proteomics : MCP 2021;20:100120
Molecular & cellular proteomics : MCP 2021;20:100120
Thyroglobulin Interactome Profiling Defines Altered Proteostasis Topology Associated With Thyroid Dyshormonogenesis.
Wright MT, Kouba L, Plate L
Molecular & cellular proteomics : MCP 2021;20:100008
Molecular & cellular proteomics : MCP 2021;20:100008
Comparative host interactomes of the SARS-CoV-2 nonstructural protein 3 and human coronavirus homologs.
Almasy KM, Davies JP, Plate L
bioRxiv : the preprint server for biology 2021 Mar 8;
bioRxiv : the preprint server for biology 2021 Mar 8;
A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes.
Chhabra NF, Amend AL, Bastidas-Ponce A, Sabrautzki S, Tarquis-Medina M, Sachs S, Rubey M, Lorenz-Depiereux B, Feuchtinger A, Bakhti M, Lickert H, Przemeck GKH, Hrabě de Angelis M
Molecular metabolism 2021 Dec;54:101334
Molecular metabolism 2021 Dec;54:101334
Identification and detection of mecciRNAs.
Liu X, Yang Y, Shan G
Methods (San Diego, Calif.) 2021 Dec;196:147-152
Methods (San Diego, Calif.) 2021 Dec;196:147-152
Identification of mecciRNAs and their roles in the mitochondrial entry of proteins.
Liu X, Wang X, Li J, Hu S, Deng Y, Yin H, Bao X, Zhang QC, Wang G, Wang B, Shi Q, Shan G
Science China. Life sciences 2020 Oct;63(10):1429-1449
Science China. Life sciences 2020 Oct;63(10):1429-1449
Comparative multiplexed interactomics of SARS-CoV-2 and homologous coronavirus non-structural proteins identifies unique and shared host-cell dependencies.
Davies JP, Almasy KM, McDonald EF, Plate L
bioRxiv : the preprint server for biology 2020 Jul 14;
bioRxiv : the preprint server for biology 2020 Jul 14;
Comparative Multiplexed Interactomics of SARS-CoV-2 and Homologous Coronavirus Nonstructural Proteins Identifies Unique and Shared Host-Cell Dependencies.
Davies JP, Almasy KM, McDonald EF, Plate L
ACS infectious diseases 2020 Dec 11;6(12):3174-3189
ACS infectious diseases 2020 Dec 11;6(12):3174-3189
PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity.
Jang I, Pottekat A, Poothong J, Yong J, Lagunas-Acosta J, Charbono A, Chen Z, Scheuner DL, Liu M, Itkin-Ansari P, Arvan P, Kaufman RJ
eLife 2019 Jun 11;8
eLife 2019 Jun 11;8
Quantitative Interactome Proteomics Reveals a Molecular Basis for ATF6-Dependent Regulation of a Destabilized Amyloidogenic Protein.
Plate L, Rius B, Nguyen B, Genereux JC, Kelly JW, Wiseman RL
Cell chemical biology 2019 Jul 18;26(7):913-925.e4
Cell chemical biology 2019 Jul 18;26(7):913-925.e4
N-Glycosylation is required for FDNC5 stabilization and irisin secretion.
Nie Y, Liu D
The Biochemical journal 2017 Sep 7;474(18):3167-3177
The Biochemical journal 2017 Sep 7;474(18):3167-3177
Expression of protein disulfide isomerase family members correlates with tumor progression and patient survival in ovarian cancer.
Samanta S, Tamura S, Dubeau L, Mhawech-Fauceglia P, Miyagi Y, Kato H, Lieberman R, Buckanovich RJ, Lin YG, Neamati N
Oncotarget 2017 Nov 28;8(61):103543-103556
Oncotarget 2017 Nov 28;8(61):103543-103556
Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation.
Plate L, Cooley CB, Chen JJ, Paxman RJ, Gallagher CM, Madoux F, Genereux JC, Dobbs W, Garza D, Spicer TP, Scampavia L, Brown SJ, Rosen H, Powers ET, Walter P, Hodder P, Wiseman RL, Kelly JW
eLife 2016 Jul 20;5
eLife 2016 Jul 20;5
Mapping wild-type and R345W fibulin-3 intracellular interactomes.
Hulleman JD, Genereux JC, Nguyen A
Experimental eye research 2016 Dec;153:165-169
Experimental eye research 2016 Dec;153:165-169
Identification and characterization of an endoplasmic reticulum localization motif.
Nie YW, Wang M, Zhang P, Huan L, Liu DJ
Biochemical and biophysical research communications 2016 Apr 22;473(1):249-254
Biochemical and biophysical research communications 2016 Apr 22;473(1):249-254
MicroRNA directly enhances mitochondrial translation during muscle differentiation.
Zhang X, Zuo X, Yang B, Li Z, Xue Y, Zhou Y, Huang J, Zhao X, Zhou J, Yan Y, Zhang H, Guo P, Sun H, Guo L, Zhang Y, Fu XD
Cell 2014 Jul 31;158(3):607-19
Cell 2014 Jul 31;158(3):607-19
Inhibition by imatinib of expression of O-glycan-related glycosyltransferases and tumor-associated carbohydrate antigens in the K562 human leukemia cell line.
Sun QC, Liu MB, Shen HJ, Jiang Z, Xu L, Gao LP, Ni JL, Wu SL
Asian Pacific journal of cancer prevention : APJCP 2013;14(4):2447-51
Asian Pacific journal of cancer prevention : APJCP 2013;14(4):2447-51
Receptor-like protein-tyrosine phosphatase α enhances cell surface expression of neural adhesion molecule NB-3.
Ye H, Zhao T, Tan YL, Liu J, Pallen CJ, Xiao ZC
The Journal of biological chemistry 2011 Jul 22;286(29):26071-80
The Journal of biological chemistry 2011 Jul 22;286(29):26071-80
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 14712-1-AP(PDIA4 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of PC-3 cells, using PDIA4 antibody 14712-1-AP at 1:50 dilution and FITC-labeled donkey anti-rabbit IgG (green).
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung cancer using 14712-1-AP(PDIA4 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung cancer using 14712-1-AP(PDIA4 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue