BS6942

antibody from Bioworld Technology, Inc
Targeting: CHIA AMCase, CHIT2, TSA1902
Provider product page for BS6942
Western blot
Immunohistochemistry

Antibody data

Product number
BS6942 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CHIA polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CHIA.
Description
Chitinases are ubiquitous chitin-fragmenting hydrolases. The chitinase Chitotriosidase is capable of cleaving natural chitin and chitin-like substrates in humans and may play a role in immunity against pathogens containing chitin. Activated human macrophages secrete chitotriosidase, and increased plasma levels of chitotriosidase are a feature of patients suffering from Gaucher£ªs disease. Expression of mouse Chitotriosidase is restricted to brain, skin, bone marrow, kidney, tongue, stomach and testis. The homology between chitotriosidase and chitinases found in lower organisms is significant. Acidic mammalian chitinase precursor (AMCase) degrades chitotriose and chitin. AMCase is highly expressed in stomach tissues and is primarily a secreted protein. It is involved in Th2-mediated inflammation and may play a role in asthma and allergic diseases.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CHIA protein structure - BS6942 shown in red.