Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB2415 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2415, RRID:AB_1580450
- Product name
- SENP2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of SENP2.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex.
Association of the human SUMO-1 protease SENP2 with the nuclear pore.
Characterization of a novel mammalian SUMO-1/Smt3-specific isopeptidase, a homologue of rat axam, which is an axin-binding protein promoting beta-catenin degradation.
Zhang H, Saitoh H, Matunis MJ
Molecular and cellular biology 2002 Sep;22(18):6498-508
Molecular and cellular biology 2002 Sep;22(18):6498-508
Association of the human SUMO-1 protease SENP2 with the nuclear pore.
Hang J, Dasso M
The Journal of biological chemistry 2002 May 31;277(22):19961-6
The Journal of biological chemistry 2002 May 31;277(22):19961-6
Characterization of a novel mammalian SUMO-1/Smt3-specific isopeptidase, a homologue of rat axam, which is an axin-binding protein promoting beta-catenin degradation.
Nishida T, Kaneko F, Kitagawa M, Yasuda H
The Journal of biological chemistry 2001 Oct 19;276(42):39060-6
The Journal of biological chemistry 2001 Oct 19;276(42):39060-6
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of SENP2 polyclonal antibody (Cat # PAB2415) in HL-60 cell lysate. SENP2 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with the SENP2 polyclonal antibody (Cat # PAB2415) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)