H00026191-B01

antibody from Abnova Corporation

Targeting: PTPN22 Lyp, Lyp1, Lyp2, PTPN8

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

H00026191-B01

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#H00026191-B01, RRID:AB_1115096

Product name

PTPN22 MaxPab mouse polyclonal antibody (B01)

Antibody type

Polyclonal

Description

Mouse polyclonal antibody raised against a full-length human PTPN22 protein.

Antigen sequence

MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQS
TKYKADKTYPTTVAEKPKNIKKNRYKDILPYDYSR
VELSLITSDEDSSYINANFIKGVYGPKAYIATQGP
LSTTLLDFWRMIWEYSVLIIVMACMEYEMGKKKCE
RYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLK
VKFNSETRTIYQFHYKNWPDHDVPSSIDPILELIW
DVRCYQEDDSVPICIHCSAGCGRTGVICAIDYTWM
LLKDGSQAKHCIPEKNHTLQADSYSPNLPKSTTKA
AKMMNQQRTKMEIKESSSFDFRTSEISAKEELVLH
PAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIV
GEPLQKHQSLDLGSLLFEGCSNSKPVNAAGRYFNS
KVPITRTKSTPFELIQQRETKEVDSKENFSYLESQ
PHDSCFVEMQAQKVMHVSSAELNYSLPYDSKHQIR
NASNVKHHDSSALGVYSYIPLVENPYFSSWPPSGT
SSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNS
HDSLSLNSPTNISSLLNQESAVLATAPRIDDEIPP
PLPVRTPESFIVVEEAGEFSPNVPKSLSSAVKVKI
GTSLEWGGTSEPKKFDDSVILRPSKSVKLRSPKSE
LHQDRSSPPPPLPERTLESFFLADEDCMQAQSIET
YSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKIL
RNMKKSICNSCPPNKPAESVQSNNSSSFLNFGFAN
RFSKPKGPRNPPPTWNI


Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References

Submitted references

High basal activity of the PTPN22 gain-of-function variant blunts leukocyte responsiveness negatively affecting IL-10 production in ANCA vasculitis.

Cao Y, Yang J, Colby K, Hogan SL, Hu Y, Jennette CE, Berg EA, Zhang Y, Jennette JC, Falk RJ, Preston GA
PloS one 2012;7(8):e42783

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western Blot analysis of PTPN22 expression in transfected 293T cell line (H00026191-T01) by PTPN22 MaxPab polyclonal antibody.Lane1:PTPN22 transfected lysate(82.72 KDa).Lane2:Non-transfected lysate.