BS5626

antibody from Bioworld Technology, Inc
Targeting: BCAS2 DAM1, Snt309, SPF27
Provider product page for BS5626
Western blot
Immunoprecipitation

Antibody data

Product number
BS5626 - Provider product page
Provider
Bioworld Technology, Inc
Product name
BCAS2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 180-225 of Human BCAS2.
Description
BCAS2 (breast carcinoma amplified sequence 2), also designated DAM1 (DNA amplified in mammary carcinoma 1 protein) or spliceosome-associated SPF 27, is a ubiquitously expressed nuclear protein that was originally identified as being overexpressed in various breast cancer cell lines. BCAS2 is now known to be a component of the spliceosome, participating in the removal of introns from mRNA precursors. BCAS2 specifically interacts (in a ligandindependent manner) with TRÉÇ (thyroid hormone receptor ÉÇ), ERÏ« (estrogen receptor Ï«), ERÉÇ, PR (progesterone receptor), and PPARÎÛ (Peroxisome proliferator-activated receptor ÎÛ). BCAS2 functions as an ER coactivator and is capable of enhancing ER-mediated transcription. This suggests that BCAS2 is involved in the development of breast cancer.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
BCAS2 protein structure - BS5626 shown in red.