Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 675002 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#675002, RRID:AB_2565487
- Product name
- Purified anti-Leptin
- Antibody type
- Monoclonal
- Antigen
- Recombinant human Leptin.
- Description
- Leptin is primarily synthesized from adipocytes and plays a major role in energy homeostasis and obesity. Leptin resistance has been proposed as a pathophysiological mechanism of obesity. In obese individuals, expression of the short form of the leptin receptor, Ob-Ra, is downregulated, and the individual may be unresponsive to leptin signals. Leptin has also been implicated in the regulation of reproduction, glucose homeostasis, bone formation, hematopoiesis, and wound healing.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- M1905E01
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Western blot analysis of recombinant human leptin 25 ng (lane 1), and 50ng (lane 2) using anti-Leptin antibody (clone M1905E01) and HRP anti-mouse IgG antibody.
- Conjugate
- Unconjugated