Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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Comment
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- Product number
- PAB4576 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB4576, RRID:AB_1579113
- Product name
- PRKAB2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of PRKAB2.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus.
Effects of thyroid state on AMP-activated protein kinase and acetyl-CoA carboxylase expression in muscle.
Variant screening of PRKAB2, a type 2 diabetes mellitus susceptibility candidate gene on 1q in Pima Indians.
Minokoshi Y, Alquier T, Furukawa N, Kim YB, Lee A, Xue B, Mu J, Foufelle F, Ferré P, Birnbaum MJ, Stuck BJ, Kahn BB
Nature 2004 Apr 1;428(6982):569-74
Nature 2004 Apr 1;428(6982):569-74
Effects of thyroid state on AMP-activated protein kinase and acetyl-CoA carboxylase expression in muscle.
Park SH, Paulsen SR, Gammon SR, Mustard KJ, Hardie DG, Winder WW
Journal of applied physiology (Bethesda, Md. : 1985) 2002 Dec;93(6):2081-8
Journal of applied physiology (Bethesda, Md. : 1985) 2002 Dec;93(6):2081-8
Variant screening of PRKAB2, a type 2 diabetes mellitus susceptibility candidate gene on 1q in Pima Indians.
Prochazka M, Farook VS, Ossowski V, Wolford JK, Bogardus C
Molecular and cellular probes 2002 Dec;16(6):421-7
Molecular and cellular probes 2002 Dec;16(6):421-7
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The PRKAB2 polyclonal antibody (Cat # PAB4576) is used in Western blot to detect PRKAB2 in mouse brain tissue lysate .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with PRKAB2 polyclonal antibody (Cat # PAB4576) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . BC = breast carcinoma .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)