Antibody data
- Antibody Data
- Antigen structure
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- Product number
- Ab106387 - Provider product page
- Provider
- Aladdin Scientific Corporation
- Product name
- GRB2 Mouse mAb
- Antibody type
- Monoclonal
- Description
- PurityProtein A purifiedTested applicationsSuitable for: WB , Flow Cyt (Intra) , IP , IHC-P , ICC/IF more detailsFunctionAdapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Isoform GRB3-3 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform GRB3-3 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
AA 1-217
- Antibody clone number
- 5G3-E7-F11
- Vial size
- 100μl,10μl,1ml,50μl
- Concentration
- 4,2 mg/ml
- Storage
- Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
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