Ab106387

antibody from Aladdin Scientific Corporation
Targeting: GRB2 NCKAP2
Provider product page for Ab106387
Western blot

Antibody data

Product number
Ab106387 - Provider product page
Provider
Aladdin Scientific Corporation
Product name
GRB2 Mouse mAb
Antibody type
Monoclonal
Description
PurityProtein A purifiedTested applicationsSuitable for: WB , Flow Cyt (Intra) , IP , IHC-P , ICC/IF more detailsFunctionAdapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Isoform GRB3-3 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform GRB3-3 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.
Reactivity
Human, Mouse, Rat
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
AA 1-217
Antibody clone number
5G3-E7-F11
Vial size
100μl,10μl,1ml,50μl
Concentration
4,2 mg/ml
Storage
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
GRB2 protein structure - Ab106387 shown in red.